TCI B6801 (CAS 3035177-77-3) is N,N'-bis(2-phenyl-1-naphthyl)-1,2-benzenediamine, an aromatic diamine bearing two highly bulky naphthyl substituents. Its ortho-phenylenediamine core is well suited to cyclisation toward benzimidazolium salts and, in turn, N-heterocyclic carbene ligands. The bulky aryl walls allow chemists to tune the steric environment around a metal centre in organometallic catalyst design. AMI Scientific offers this TCI reagent in 250 mg and 1 g pack sizes; store it cool, dark, and tightly closed, as aromatic diamines may darken on air exposure.
Advantages (TCI brochure)
- C(sp2)-O cross coupling
- C(sp2)-N cross coupling with a weak base, NaOTMS
- Effective for base-sensitive five-membered heteroarenes as substrates
- Allows switching N/O selectivity depending on base
TCI brochures (PDF)
- Copper(II) Complex Catalyst for Ullmann-type C(sp2)-O/N Cross-Coupling Reactions without Degassing 2025-09-12 · p. 1
- Diamine Ligands for Ullmann-Type Cross-Coupling at Room Temperature 2024-12-23 · p. 1
- Ligands 2025-12-01 · p. 10
Related TCI products
- TCI B3114 673-40-5 4-Bromobenzenediazonium Tetrafluoroborate
- TCI M2636 459-64-3 4-Methoxybenzenediazonium Tetrafluoroborate
- TCI N0869 1465-25-4 N-(1-Naphthyl)ethylenediamine Dihydrochloride [for Biochemical Research]
- TCI N0577 N-(1-Naphthyl)ethylenediamine Dihydrochloride Monomethanolate
- TCI N0063 1465-25-4 N-(1-Naphthyl)ethylenediamine Dihydrochloride
- TCI I0125 86-84-0 1-Naphthyl Isocyanate
From the TCI brochure
- C(sp2)-O cross-coupling of aryl bromides with alcohols
- C(sp2)-N cross-coupling with base-sensitive five-membered heteroarenes
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