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Description
TCI B6805 1-(2-Bromoethyl)pyrrolidin-2-one (CAS 117018-99-2) is a versatile alkylating building block combining a five-membered lactam ring with a reactive primary bromide. The bromoethyl chain readily undergoes nucleophilic substitution with amines, thiols, phenols, and stabilised carbanions, installing the 2-pyrrolidinone motif in a single step. This makes it a practical intermediate for medicinal chemistry, compound library synthesis, and the grafting of polar amide groups onto larger scaffolds. Offered in 1 g and 5 g packs, it should be handled in a fume hood and stored cool, dry, and away from strong bases and other nucleophiles.
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