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TCI

CAS 98-60-2

4-Chlorobenzenesulfonyl Chloride TCI C0128

4-Chlorobenzenesulfonyl Chloride TCI C0128

Chemical Identity

Other names
4-Chlorophenylsulfonyl Chloride
CAS No.
98-60-2
Formula
C6H4Cl2O2S
Molecular weight
211.06 g/mol
Purity
>98.0%(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
4-chlorobenzenesulfonyl chloride
SMILES
C1=CC(=CC=C1S(=O)(=O)Cl)Cl
InChIKey
ZLYBFBAHAQEEQQ-UHFFFAOYSA-N
MDL
MDL00007439
PubChem
CID 7398
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TCI C0128 4-Chlorobenzenesulfonyl Chloride (CAS 98-60-2) is a classic sulfonylating reagent for forming sulfonamides and sulfonate esters. It reacts readily with amines, alcohols, and phenols, making it central to medicinal chemistry programmes where the sulfonamide motif is common. The arylsulfonyl group also serves as a convenient nitrogen protecting group in multistep synthesis. Supplied by TCI in 25 g and 500 g packs, the reagent is moisture sensitive and must be handled under dry conditions in a fume hood.

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  • Petrova et al. (2008). Electron diffraction and quantum-chemical study of the molecular structure of 2-chlorobenzenesulfonyl chloride. Journal of Structural Chemistry doi:10.1007/s10947-008-0147-8

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.