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Description
TCI C0128 4-Chlorobenzenesulfonyl Chloride (CAS 98-60-2) is a classic sulfonylating reagent for forming sulfonamides and sulfonate esters. It reacts readily with amines, alcohols, and phenols, making it central to medicinal chemistry programmes where the sulfonamide motif is common. The arylsulfonyl group also serves as a convenient nitrogen protecting group in multistep synthesis. Supplied by TCI in 25 g and 500 g packs, the reagent is moisture sensitive and must be handled under dry conditions in a fume hood.
Scientific References
Petrova et al. (2008). Electron diffraction and quantum-chemical study of the molecular structure of 2-chlorobenzenesulfonyl chloride. Journal of Structural Chemistrydoi:10.1007/s10947-008-0147-8
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
