TCI 4-(Chloroacetyl)catechol (CAS 99-40-1) is a catechol derivative bearing a reactive chloroacetyl group, offering two complementary reaction sites in a single molecule. The α-haloketone moiety readily undergoes nucleophilic substitution with amines and thiols, while the catechol core is a well-known structural motif in biologically active compounds. Available in a 25 g package, it fits research-scale synthesis and medicinal chemistry intermediate preparation. Weigh and handle the material in a fume hood with suitable protective equipment, and keep the container tightly closed in a cool, dry, light-protected place.
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- Guo et al. (2012). Inactivating hemocyanin from Oncomelania hupensis with 4-(chloroacetyl)catechol and its application in snail control. Pesticide Biochemistry and Physiology doi:10.1016/j.pestbp.2012.01.006
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