TCI C1277 3-Chloroacetylacetone (CAS 1694-29-7) is a halogenated 1,3-diketone widely used for heterocycle construction. Its activated chlorine reacts readily with thioureas, thioamides, and nitrogen nucleophiles to give thiazole, imidazole, and related azole rings. The 1,3-dicarbonyl motif also makes it relevant to coordination chemistry and metal chelate studies. AMI Scientific offers this TCI reagent in a 25 g pack size for synthetic research.
TCI brochures (PDF)
- Ligands 2025-12-01 · p. 18
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- Zaware et al. (2022). Kinetics of Ring Closure Thiazole Cyclization Using 3-Chloroacetylacetone with Thioamides. Current Physical Chemistry doi:10.2174/1877946812666220928101610
- Kianfara et al. (2010). Synthesis and electrochemistry of M(II) N2O2 schiff base complexes: X-Ray structure of {Ni[Bis(3-chloroacetylacetone)ethylenediimine]}. Journal of the Iranian Chemical Society doi:10.1007/bf03246087
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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