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Description
TCI C0387 Cyclopropanecarboxylic Acid, CAS 1759-53-1, is a liquid carboxylic acid building block bearing the increasingly popular cyclopropyl motif. It is readily converted into acid chlorides, esters, amides, and other derivatives, making it a convenient entry point for introducing a conformationally rigid three-membered ring. Common applications include medicinal chemistry research, agrochemical intermediates, and heterocycle synthesis. Supplied by AMI Scientific in 25 mL, 100 mL, and 500 mL sizes, it is corrosive and should be handled in a fume hood with appropriate protective equipment and stored tightly closed in a cool, dry, well-ventilated area.
Scientific References
Akimov et al. (2025). Theoretical conformational analysis of cyclopropanecarboxylic acid fluoride and cyclopropanecarboxylic acid chloride in lowest excited electronic states and investigation of possible torsion–inversion coupling. Computational and Theoretical Chemistrydoi:10.1016/j.comptc.2025.115435
Pejlovas et al. (2015). Microwave spectra and structure of the cyclopropanecarboxylic acid-formic acid dimer. The Journal of Chemical Physicsdoi:10.1063/1.4931923
Vereshchagin et al. (2016). ChemInform Abstract: The First Electrocatalytic Stereoselective Multicomponent Synthesis of Cyclopropanecarboxylic Acid Derivatives.. ChemInformdoi:10.1002/chin.201615072
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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