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Description
TCI C0470 Cyclohexanecarboxylic Acid (CAS 98-89-5) is an alicyclic carboxylic acid that serves as a versatile non-heterocyclic building block. Its carboxyl group readily undergoes esterification, amidation, reduction, and activation to acyl derivatives, while the cyclohexane ring introduces a saturated three-dimensional motif into target molecules. This makes it particularly useful in medicinal chemistry programmes that replace flat aromatic rings with saturated scaffolds. Supplied in 25 g and 500 g packs, it should be stored in a cool, dry place in a tightly closed container, away from strong bases and oxidising agents.
Scientific References
Liu et al. (1994). Pharmacokinetics and Pharmacodynamics of Valproate Analogues in Rats. IV. Anticonvulsant Action and Neurotoxocity of Octanoic Acid, Cyclohexanecarboxylic Acid, and 1‐Methyl‐1 ‐Cyclohexanecarboxylic Acid. Epilepsiadoi:10.1111/j.1528-1157.1994.tb02939.x
Liu et al. (1992). Pharmacokinetics and pharmacodynamics of valproate analogs in rats. III. Pharmacokinetics of valproic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid in the bile-exteriorized rat.. Drug Metabolism and Dispositiondoi:10.1016/s0090-9556(25)08799-9
Liu et al. (1993). Pharmacokinetics and pharmacodynamics of valproate analogs in rats. II. Pharmacokinetics of octanoic acid, cyclohexanecarboxylic acid, and 1‐methyl‐1‐cyclohexanecarboxylic acid. Biopharmaceutics & Drug Dispositiondoi:10.1002/bdd.2510140406
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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