TCI C0998 (+)-10-Camphorsulfonyl Chloride (CAS 21286-54-4) is a classic chiral building block that pairs the rigid, optically active camphor skeleton with a highly reactive sulfonyl chloride group. It is widely used as a chiral derivatizing agent, converting amines and alcohols into separable diastereomers for enantiomeric purity determination by HPLC or NMR. The same scaffold also serves as an entry point to camphorsultam-type chiral auxiliaries that direct stereoselectivity in alkylation and cycloaddition chemistry. AMI Scientific offers 5 g and 25 g packs; because the reagent is strongly moisture sensitive, handle it in a fume hood and store it tightly sealed in a cool, dry place, preferably under inert gas.
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- KO et al. (1998). ChemInform Abstract: A Convenient Preparation of (1S)‐(+)‐10‐Mercaptoisoborneol from (1S)‐(+)‐10‐Camphorsulfonyl Chloride with High Diastereoselectivity.. ChemInform doi:10.1002/chin.199837217
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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