Chlorhexidine Dihydrochloride TCI C1254

Chemical Identity

Other names: 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] Dihydrochloride
CAS No.: 3697-42-5
PubChem: CID 9571016·SID 87566273
Formula: C22H30Cl2N10.2HCl
Molecular weight: 578.37 g/mol
Purity: >96.0%(T)
Reference databases: ChEBI·ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;dihydrochloride
SMILES: C1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl)N)N)Cl.Cl.Cl
InChIKey: WJLVQTJZDCGNJN-UHFFFAOYSA-N
MDL: MDL00068998

Rp 1.192.800,00

~~Rp 849.450,00~~ Rp 1.192.800,00

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Berat 5g 25g

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TCI C1254 Chlorhexidine Dihydrochloride (CAS 3697-42-5) is a cationic bisbiguanide antimicrobial supplied as a research reagent under the antibiotics category. Its positively charged biguanide groups interact strongly with negatively charged microbial membranes, making it a standard reference antiseptic in susceptibility and biofilm studies. Laboratories also use it as a model active ingredient in antiseptic formulation, dental materials, and antimicrobial surface coating research. AMI Scientific offers 5 g and 25 g pack sizes for experimental use only, and dust inhalation should be avoided during weighing.

TCI brochures (PDF)

Antibiotic Ingredients for Drug-Resistant Pathogens 2026-10-01 · p. 1
Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 7
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 7

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Andersen (1999). Note Regarding the Safety Assessment of Chlorhexidine, Chlorhexidine Diacetate, Chlorhexidine Digluconate, and Chlorhexidine Dihydrochloride. International Journal of Toxicology doi:10.1177/109158189901800209
(1993). Final Report on the Safety Assessment of Chlorhexidine/Chlorhexidine Diacetate/Chlorhexidine Dihydrochloride/Chlorhexidine Digluconate. Journal of the American College of Toxicology doi:10.3109/10915819309140642
Gaffar et al. (2009). Effects of Chlorhexidine Dihydrochloride in the Diet on Caries in Hamsters. Caries Research doi:10.1159/000260440

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.