TCI C1282 4-Chlorosalicylic Acid (CAS 5106-98-9) is a chlorinated salicylic acid derivative bearing adjacent carboxyl and phenolic hydroxyl groups. This ortho arrangement supports ester and amide formation, phenol functionalisation, and chelate-type metal coordination. The scaffold is applied in pharmaceutical intermediate research, heterocycle synthesis, and structure–activity studies. AMI Scientific supplies this TCI reagent in a 25 g pack size for laboratory use.
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- Sofia (2008). Comparative Antiphlogistic Activity of Meseclazone, 5-Chlorosalicylic Acid, Acetylsalicylic Acid, Phenylbutazone, Indomethacin and Hydrocortisone in Various Rat Paw Edema Models. Pharmacology doi:10.1159/000136760
- Kök (2020). Improving of callus formation in ‘Syrah’/‘110R’ combination by 5-chlorosalicylic acid and thidiazuron treatments. Acta Horticulturae doi:10.17660/actahortic.2020.1276.14
- Dr.Hemendra H Bhatt (2020). A Photophysical and Computational Study of 5-Chlorosalicylic Acid and Derivatives Featuring Thiadiazole, Oxadiazole, and Triazole Scaffolds. Vidhyayana doi:10.58213/9k1rtq07
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