N-Benzyloxycarbonyl-L-threonine TCI C1351

Chemical Identity

Other names: N-Cbz-L-threonine · Z-Thr-OH · N-Carbobenzoxy-L-threonine
CAS No.: 19728-63-3
PubChem: CID 88217·SID 87566363
Formula: C12H15NO5
Molecular weight: 253.25 g/mol
Purity: >98.0%(HPLC)(T)
Reference databases: ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2S,3R)-3-hydroxy-2-(phenylmethoxycarbonylamino)butanoic acid
SMILES: CC(C(C(=O)O)NC(=O)OCC1=CC=CC=C1)O
InChIKey: IPJUIRDNBFZGQN-SCZZXKLOSA-N
MDL: MDL00065948

Rp 2.386.650,00

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TCI C1351 N-Benzyloxycarbonyl-L-threonine (CAS 19728-63-3), commonly known as Z-L-Thr-OH, is an amino-protected threonine derivative for peptide chemistry. The benzyloxycarbonyl group is removed under neutral hydrogenolysis conditions, making it fully orthogonal to acid- and base-labile protecting groups such as Boc and Fmoc. It is routinely used in solution-phase peptide synthesis, glycopeptide fragment preparation, and the construction of modified peptide analogues. AMI Scientific supplies this TCI reagent in a 10 g pack size for research laboratories.

TCI brochures (PDF)

Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 18

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Delacotte et al. (1992). Oxidation, With Chiral Retention, of Benzyloxycarbonyl Threonine Methyl Ester. Synthetic Communications doi:10.1080/00397919209409256

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.