TCI C1354 N-Benzyloxycarbonyl-L-isoleucine (CAS 3160-59-6), also known as Z-L-Ile-OH, is a Cbz-protected derivative of the branched-chain amino acid L-isoleucine. The benzyloxycarbonyl group is cleaved by catalytic hydrogenolysis under neutral conditions, keeping it orthogonal to acid- and base-labile protecting strategies. It is widely used in solution-phase peptide synthesis, bioactive peptide fragment preparation, and peptidomimetic design where a hydrophobic branched residue is required. AMI Scientific supplies this TCI reagent in 5 g and 25 g pack sizes for research use.
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