TCI C1354 N-Benzyloxycarbonyl-L-isoleucine (CAS 3160-59-6), also known as Z-L-Ile-OH, is a Cbz-protected derivative of the branched-chain amino acid L-isoleucine. The benzyloxycarbonyl group is cleaved by catalytic hydrogenolysis under neutral conditions, keeping it orthogonal to acid- and base-labile protecting strategies. It is widely used in solution-phase peptide synthesis, bioactive peptide fragment preparation, and peptidomimetic design where a hydrophobic branched residue is required. AMI Scientific supplies this TCI reagent in 5 g and 25 g pack sizes for research use.
TCI brochures (PDF)
- Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 18
Related TCI products
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![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-isoleucine (CAS 138775-22-1) - TCI F1129 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510F1129.jpg?v=1768205441&width=533)
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS 71989-23-6) - TCI F0294 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510F0294.jpg?v=1769180798&width=533)





