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TCI

CAS 3160-59-6

N-Benzyloxycarbonyl-L-isoleucine TCI C1354

N-Benzyloxycarbonyl-L-isoleucine TCI C1354

Chemical Identity

Other names
Z-Ile-OH · N-Cbz-L-isoleucine · Z-Ile-OH · N-Carbobenzoxy-L-isoleucine
CAS No.
3160-59-6
PubChem
CID 2724772·SID 87566366
Formula
C14H19NO4
Molecular weight
265.31 g/mol
Purity
>98.0%(HPLC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid
SMILES
CCC(C)C(C(=O)O)NC(=O)OCC1=CC=CC=C1
InChIKey
JSHXJPFZKBRLFU-JQWIXIFHSA-N
MDL
MDL00027064
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TCI C1354 N-Benzyloxycarbonyl-L-isoleucine (CAS 3160-59-6), also known as Z-L-Ile-OH, is a Cbz-protected derivative of the branched-chain amino acid L-isoleucine. The benzyloxycarbonyl group is cleaved by catalytic hydrogenolysis under neutral conditions, keeping it orthogonal to acid- and base-labile protecting strategies. It is widely used in solution-phase peptide synthesis, bioactive peptide fragment preparation, and peptidomimetic design where a hydrophobic branched residue is required. AMI Scientific supplies this TCI reagent in 5 g and 25 g pack sizes for research use.

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