TCI C1381 N-Benzyloxycarbonyl-O-tert-butyl-L-serine (Z-Ser(tBu)-OH, CAS 1676-75-1) is a doubly protected amino acid derivative for peptide chemistry. The Z group masks the alpha amine while the tert-butyl ether protects the serine side chain, giving a practical orthogonal protection scheme. This combination suppresses side reactions during coupling and allows selective deprotection at the right stage of a synthesis. AMI Scientific supplies this TCI building block in 1 g and 5 g packs for solution-phase peptide and chemical biology work.
TCI brochures (PDF)
- Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 18
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