TCI C1437 2-Chlorocyclopentanone (CAS 694-28-0) is an alpha-halo cyclic ketone supplied stabilized with hydroquinone (HQ) and calcium carbonate (CaCO3). The activated alpha-chlorine is readily displaced by amines, thiols, and stabilized carbanions, making it a classic starting material for heterocycle construction such as thiazoles and imidazoles. Its ketone group can be further functionalized through reduction or nucleophilic addition, giving the reagent dual reactivity in complex molecule synthesis. AMI Scientific offers this TCI building block in 5 g and 25 g packages for research use.
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