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TCI

CAS 75621-03-3

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate TCI C1578

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate TCI C1578
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Description

TCI C1578 CHAPS (CAS 75621-03-3) is a zwitterionic, bile-acid-derived surfactant widely used for the gentle solubilisation of hydrophobic components. Its steroid backbone paired with a dual-charged head group gives it strong solubilising power while remaining net-neutral in charge under common working conditions. Typical applications include membrane protein extraction, two-dimensional electrophoresis sample preparation, buffer formulation, and polymer interface studies. AMI Scientific offers this TCI reagent in convenient 1 g and 5 g packages; please refer to the official TCI documentation for full technical and safety information.

Scientific References

  • Tornel et al. (1991). Inhibition of cholinesterases by the zwitterionic detergent 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS). Bioorganic Chemistry doi:10.1016/0045-2068(91)90038-q
  • Nomura (2001). Incomplete Dialysis of Protein Samples Containing 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate May Lead to Erroneous Estimation of Histidine Content on Amino Acid Analysis. Analytical Biochemistry doi:10.1006/abio.2000.4971
  • Shnigir et al. (2004). Transformation of Phospholipids by Cabbage Phospholipase D in Mixed Micelles Containing 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate. Applied Biochemistry and Microbiology doi:10.1023/b:abim.0000025942.11918.39

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.

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