4-(4-Chlorophenyl)morpholine TCI C2082

Name: TCI C2082 70291-67-7 4-(4-Chlorophenyl)morpholine
Brand: TCI
SKU: TCI2510C208216736
Price: 1949850.0 IDR
Availability: InStock

Rp 1.949.850,00

Sale Sold out

Shipping calculated at checkout.

Berat 5g

Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.

Description

TCI C2082 4-(4-Chlorophenyl)morpholine is a compound that joins a morpholine ring to a chlorine-substituted benzene ring through a carbon–nitrogen bond. Morpholine is a six-membered heterocycle containing one nitrogen atom and one oxygen atom, and it ranks among the most frequently encountered motifs in the structures of drug compounds. As a heterocyclic building block, this material supplies chemists with a ready-made fragment, so the often time-consuming aryl–amine bond-forming step does not need to be repeated and synthetic effort can be directed straight at modifying other parts of the molecule.

The main appeal of this compound lies in the character of the morpholine ring, which provides a balance between polarity and solubility. The ring oxygen lowers the basicity of the nitrogen compared with an ordinary cyclic amine, so this fragment is frequently used to improve the physicochemical properties of a target molecule without adding excessive molecular weight. The chlorine group on the aromatic ring acts as a reactive handle for transition-metal-catalysed cross-coupling reactions, while at the same time exerting an electronic influence that can be exploited in structure–activity relationship studies.

In Indonesian laboratories, this building block is typically found in university and institutional research groups working on organic synthesis and medicinal chemistry, as well as in R&D units that prepare intermediates and reference compounds. It is generally used at bench scale for exploratory routes, method development, and the preparation of analogue series, where obtaining a defined heterocyclic fragment from a recognised supplier such as TCI shortens the route and keeps results comparable between batches of work.

Laboratory Applications

Medicinal chemistry fragment assembly — the morpholine motif is one of the most common structural elements in drug molecules, making this a directly usable starting fragment for candidate design.
Transition-metal-catalysed cross-coupling — the aromatic chlorine serves as a reactive handle for metal-catalysed coupling chemistry, allowing further aryl fragments to be attached to the existing scaffold.
Structure–activity relationship studies — the electronic influence of the chlorine substituent on the aromatic ring can be systematically exploited when comparing analogues within a compound series.
Physicochemical property tuning — the morpholine ring balances polarity and solubility, so this fragment is used to adjust target molecule properties without adding excessive molecular weight.
Synthetic route shortening — supplying the aryl–amine bond ready-formed removes a frequently time-consuming construction step, letting chemists focus their work on modifying other regions of the molecule.

Specifications

Brand: TCI (Tokyo Chemical Industry)
Product code: C2082
CAS number: 70291-67-7
Chemical name: 4-(4-Chlorophenyl)morpholine
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes: available in the standard research-scale pack sizes offered for this catalogue item; storage in a cool, dry place in the original closed container is recommended

Handling and Storage

Store the container tightly closed in a cool, dry, well-ventilated area, away from direct sunlight, heat sources, and incompatible chemicals. Keep the material in its original supplier container, or in a clean, chemically compatible and clearly labelled vessel if it must be transferred. Handle in a fume hood using standard laboratory personal protective equipment, including gloves, safety glasses, and a lab coat, and avoid the generation of dust as well as contact with skin and eyes. Reseal promptly after each use to limit exposure to moisture and air, and consult the supplier safety data sheet before first use and for disposal guidance.