Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.
Description
TCI C2088 2-Chloro-5-fluorobenzoic Acid is a substituted benzoic acid carrying a chlorine atom at the ortho position and a fluorine atom at the meta position relative to the carboxyl group. The compound belongs to the family of fluorinated building blocks that are very frequently used as starting materials in organic synthesis, particularly because the carboxylic acid group is one of the most readily elaborated functional groups available to a synthetic chemist. The presence of two different halogens on the aromatic ring gives researchers several reactive points at once, so a single starting material can be directed toward a variety of derivative molecular frameworks according to the design of the synthetic route.
The characteristic that makes this compound a preferred choice is the versatility of the carboxyl group, which can be converted into an acid chloride, ester, amide, hydrazide, and on to a range of heterocyclic rings such as oxadiazoles and benzoxazoles. The position of the chlorine adjacent to the carboxyl group opens the possibility of intramolecular cyclization reactions that are useful in forming fused ring systems, while the fluorine atom contributes the electronic effects and physicochemical properties that are widely sought after in medicinal molecule design. As a solid, the material is also relatively easy to weigh out accurately.
In Indonesian laboratories, this building block is typically handled in university research groups, pharmaceutical research units, and industrial R&D laboratories working on organic synthesis and the preparation of heterocyclic compounds. It is generally weighed on an analytical balance, dissolved in a suitable organic solvent, and carried into multi-step reaction sequences. Supplied by AMI Scientific as a TCI-branded product, it fits routine synthetic workflows where a defined halogenated aromatic starting material is required.
Laboratory Applications
- Fluorinated building block supply for organic synthesis, providing a defined halogenated aromatic scaffold that can be directed toward many different derivative frameworks in a planned synthetic route.
- Carboxyl group derivatization, where the acid function is converted into acid chlorides, esters, amides, or hydrazides as intermediates for further reaction steps in the laboratory.
- Heterocycle construction, since the derivatized carboxyl group serves as the entry point to ring systems such as oxadiazoles and benzoxazoles commonly targeted in synthetic programmes.
- Intramolecular cyclization studies, because the chlorine sits adjacent to the carboxyl group and can participate in ring closure leading to fused ring systems.
- Medicinal chemistry research, where the fluorine substituent contributes electronic effects and physicochemical properties that are frequently exploited during the design of candidate drug molecules.
Specifications
- Brand: TCI
- Product code: C2088
- CAS number: 2252-50-8
- Category: Chemistry > Building Blocks > Fluorinated Building Blocks
- Physical form: solid, allowing straightforward and accurate weighing
- Pack sizes: available in the pack sizes offered for this catalogue item; storage in accordance with the manufacturer's instructions on the product label
Handling and Storage
Store the material in its original tightly closed container, kept in a cool, dry, and well-ventilated place away from direct sunlight, moisture, and incompatible chemicals. Glass bottles with chemically resistant closures are suitable for repackaging or for storing prepared solutions, and containers should be clearly labelled with the compound name and CAS number. Handle the solid inside a fume hood where practical, wearing a laboratory coat, safety glasses, and chemical-resistant gloves, and avoid raising dust during weighing and transfer. Keep the container closed when not in use, clean spills promptly, and always consult the manufacturer's Safety Data Sheet before handling and before disposing of residues or contaminated materials.
![[1,1'-Biphenyl]-2-carbonyl Chloride (CAS 14002-52-9) - TCI B6543 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510B6543.jpg?v=1767093866&width=533)
![Ethyl [1,1'-Biphenyl]-4-carboxylate (CAS 6301-56-0) - TCI B6587 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510B6587.jpg?v=1767093973&width=533)
