• 4'-Chloro-3-hydroxy-2-naphthanilide (CAS 92-78-4) - TCI C2103 - AMI Scientific
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TCI

CAS 92-78-4

4'-Chloro-3-hydroxy-2-naphthanilide TCI C2103

4'-Chloro-3-hydroxy-2-naphthanilide TCI C2103
Rp 1.949.850,00
Rp 1.949.850,00
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TCI C2103 4'-Chloro-3-hydroxy-2-naphthanilide is a simple naphthanilide compound built from a 3-hydroxy-2-naphthoic acid core joined to an aniline ring carrying a single chlorine atom at the para position. It is one of the classic coupling components in azo dye chemistry and, at the same time, a useful non-heterocyclic building block for organic synthesis. Having it on the shelf makes life easier for researchers who want to prepare azo pigments, because the reactive naphthol framework is already available and only needs to be paired with a diazo component chosen according to the target colour.

The strength of this material lies in a structure that is relatively compact yet still highly reactive. The phenolic hydroxyl group activates the naphthalene core so that coupling proceeds efficiently under mildly basic conditions, while the amide group forms hydrogen bonds that reinforce the crystal packing of the resulting pigment. The single chlorine substituent at the para position exerts an electronic influence that is easy to predict, which is why this compound is frequently used as a standard reference point when researchers study the effects of more complicated substituents.

Its solid form is a further practical advantage in day-to-day laboratory work, making weighing, storage, and purification by recrystallisation techniques straightforward. In Indonesian laboratories, this profile suits university organic chemistry groups, dye and pigment research units, and industrial R&D teams that need a dependable coupling component. Because it is supplied under the TCI brand within the Chemistry > Building Blocks > Non-Heterocyclic Building Blocks category, it fits naturally into synthesis programmes that require a consistent, well-characterised starting material.

  • Azo pigment synthesis — the reactive naphthol framework couples directly with a chosen diazo component, letting researchers build a target colour without first constructing the coupling partner themselves.
  • Azo dye chemistry teaching and demonstration — its classic role as a coupling component makes it a clear, reliable example for practical classes covering diazotisation and coupling reactions.
  • Substituent effect studies — the single para chlorine gives predictable electronic behaviour, so the compound serves as a baseline against which more complex substituted analogues can be compared.
  • Non-heterocyclic building block work — the 3-hydroxy-2-naphthoic core with an anilide linkage provides a compact scaffold that organic chemists can elaborate further in multi-step synthesis routes.
  • Recrystallisation and purification practice — the solid physical form supports straightforward weighing, handling, and recrystallisation, making it convenient for method development and routine purity work.

Brand TCI
CAS number 92-78-4
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes available in the standard TCI catalogue pack sizes for this item
Physical form solid
Storage keep in a tightly closed container in a cool, dry, well-ventilated place away from light

Store the container tightly closed in a cool, dry, well-ventilated area, protected from direct sunlight and away from strong oxidising agents and sources of ignition. The original supplier container is suitable for long-term storage; if the material is transferred, use a clean, chemically compatible bottle with a secure closure and a clearly written label showing the product name and CAS number. Handle the solid in a fume hood or a well-ventilated workspace to limit dust generation, and wear a laboratory coat, chemical-resistant gloves, and safety glasses. Use clean, dry spatulas when weighing to avoid contaminating the bulk material, close the container immediately afterwards, and consult the manufacturer's safety data sheet before first use. Collect any spilled solid without raising dust and dispose of waste according to institutional chemical waste procedures.

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