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Description
TCI C3007 Cefpirome Sulfate, bearing CAS number 98753-19-6, is the sulfate salt of cefpirome, a cephalosporin-class antibiotic built on a beta-lactam core nucleus fused to a dihydrothiazine ring. In the laboratory setting, this compound serves as a reagent and reference material for microbiological research, pharmaceutical analysis, and antimicrobial resistance studies. The mechanism of action characteristic of the cephalosporin class rests on the inhibition of bacterial cell wall synthesis, which makes this compound a useful tool whenever researchers wish to observe how bacterial isolates respond to antibiotic pressure or to evaluate the performance of an analytical method.
The property that most often drives the selection of this material is its sulfate salt form, which improves solubility in aqueous media and therefore makes the preparation of stock solutions for susceptibility testing and instrumental analysis more practical and more consistent from batch to batch. The beta-lactam framework is the reactive portion of the molecule and is sensitive to hydrolysis, particularly at extreme pH values and elevated temperatures, so solutions are normally prepared fresh immediately before use. The clearly defined structure of cefpirome also makes it a sound comparator in high performance liquid chromatography work.
In Indonesian laboratories, this material is typically encountered in university research groups, pharmaceutical quality control units, and clinical microbiology facilities that carry out routine antimicrobial testing. It supports work in which a defined cephalosporin reference is required, whether the objective is to characterise the behaviour of bacterial isolates under antibiotic exposure or to verify that an analytical procedure returns reliable results. Because it is supplied as a well characterised reference substance, it fits naturally into method development and method verification activities.
Laboratory Applications
- Antimicrobial susceptibility testing: the sulfate salt dissolves readily in aqueous media, allowing accurate stock solutions to be prepared for exposing bacterial isolates to controlled antibiotic pressure.
- Antimicrobial resistance research: the compound provides a defined cephalosporin challenge agent, so investigators can study how bacterial populations respond to inhibition of cell wall synthesis.
- High performance liquid chromatography: the clearly defined structure of cefpirome makes this material a reliable comparator when establishing retention behaviour and confirming peak identity.
- Pharmaceutical analysis: as a reference substance of known identity, it supports the analytical work required to characterise cephalosporin content and evaluate analytical method performance.
- Analytical method development and verification: researchers use it to test whether a proposed procedure performs as intended, since a well characterised reference is essential for judging method reliability.
Specifications
- Brand: TCI
- CAS Number: 98753-19-6
- Category: Life Science > Biochemicals and Reagents > Antibiotics
- Chemical identity: sulfate salt of cefpirome, a cephalosporin antibiotic with a beta-lactam core fused to a dihydrothiazine ring
- Pack sizes: available in the pack sizes offered by the manufacturer for this catalogue item
- Storage note: the beta-lactam framework is sensitive to hydrolysis, so the material requires controlled storage conditions and freshly prepared solutions
Handling and Storage
Store the container in a cool, dry place, tightly closed and protected from moisture, following the storage conditions stated by the manufacturer for this catalogue item. Because the beta-lactam framework is reactive and susceptible to hydrolysis, particularly at extreme pH and elevated temperature, avoid conditions that expose the material to heat or to strongly acidic or alkaline environments. Prepare working solutions fresh immediately before use rather than holding them for extended periods. Handle the compound in a well ventilated area using appropriate personal protective equipment, including gloves, safety glasses, and a laboratory coat, and avoid generating or inhaling dust. Use clean, dry, chemically compatible containers for weighing and transfer, label all prepared solutions clearly, and dispose of residues in accordance with applicable laboratory waste procedures.
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