2,4-Dichloro-6-methoxy-1,3,5-triazine TCI D3747

Name: TCI D3747 3638-04-8 2,4-Dichloro-6-methoxy-1,3,5-triazine
Brand: TCI
SKU: TCI2510D374724103
Price: 1535100.0 IDR
Availability: InStock

Rp 1.535.100,00

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Berat 1g 5g

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Description

2,4-Dichloro-6-methoxy-1,3,5-triazine is a fine chemical from the substituted triazine family that serves as a heterocyclic building block in organic synthesis. The 1,3,5-triazine ring in this compound carries two chloro groups that are highly reactive toward nucleophilic attack, together with a single methoxy group already installed as a fixed substituent. This combination makes it a practical starting point in the laboratory when a researcher needs to construct a triazine scaffold step by step, introduce two different nucleophiles at different positions, and control the direction of the reaction without having to assemble the heterocyclic ring from scratch.

The characteristic that makes this compound a preferred choice is the graded reactivity between the chloro groups on the triazine ring. Aromatic nucleophilic substitution on this scaffold can generally be carried out sequentially by controlling temperature, base, and solvent, so that researchers can install amines, alcohols, or thiols one after another and obtain unsymmetrical triazine derivatives. The methoxy group that is already present also simplifies synthesis planning, because one position on the ring is locked in from the outset. As a solid material, it is straightforward to weigh and dispense into reaction mixtures.

In Indonesian laboratories, this reagent is typically used in university and institutional research groups working on organic synthesis, medicinal chemistry, and materials chemistry, where triazine cores are built up toward target molecules. It is generally ordered as a catalogue fine chemical in the pack sizes offered by the brand, kept as part of a working stock of heterocyclic building blocks, and drawn on for small-scale synthetic steps, method development, and the preparation of intermediates for further study.

Laboratory Applications

Stepwise construction of unsymmetrical triazine derivatives, where the two chloro positions are substituted in sequence under controlled temperature and base conditions to give defined regiochemistry.
Introduction of amine nucleophiles onto a heterocyclic core, since the chloro groups on the triazine ring readily undergo aromatic nucleophilic substitution with primary and secondary amines.
Preparation of ether-linked triazine intermediates by reaction with alcohols, taking advantage of the reactivity gradient so that one chloro group can be displaced selectively.
Synthesis of sulfur-substituted triazine analogues using thiol nucleophiles, giving access to derivatives that would be harder to obtain by building the ring from scratch.
Medicinal and materials chemistry scaffold work, where the pre-installed methoxy group locks one ring position and reduces the number of protection or planning steps required.

Specifications

Brand: TCI
CAS Number: 3638-04-8
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes: available in the catalogue pack sizes offered by TCI for this item
Physical form: solid material
Storage: store in a cool, dry place in a tightly closed original container

Handling and Storage

Store this reagent in its original tightly closed container in a cool, dry, and well-ventilated area, away from moisture, direct sunlight, and sources of heat or ignition. Because the chloro groups on the triazine ring are reactive toward nucleophiles, keep the container sealed to limit contact with atmospheric moisture and avoid storage alongside amines, alcohols, or strong bases. Handle the solid in a fume hood using gloves, safety glasses, and a laboratory coat, and weigh it out with clean dry spatulas and glassware. Avoid generating dust, and close the container promptly after each use. Dispose of residues and contaminated materials as chemical waste in accordance with institutional procedures, and consult the manufacturer's safety data sheet before use.