TCI
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Description
TCI D3908 Diosmin is a naturally occurring flavonoid glycoside that belongs to the fields of glycoscience and chemical biology. Structurally, the compound is a flavone bound to a sugar unit, combining the character of an aromatic aglycone with a carbohydrate portion. In the laboratory, Diosmin serves as both a comparison standard and a test material in natural product research, in studies of the biological activity of flavonoids, and in the development of analytical methods for determining active compound content in plant extracts and herbal-based products. This combination of roles makes it a routine item on the bench for groups working on plant-derived bioactive molecules.
The characteristic that leads researchers to select this material is its clearly defined glycosidic structure, which makes it suitable for use as an identity marker in both chromatographic and spectroscopic analysis. The sugar portion influences solubility and the behaviour of the compound in mixed-solvent systems, while the flavone framework provides a chromophore that responds well to ultraviolet detectors. As a TCI product supplied at research reagent quality, the compound helps confirm that a peak observed on an instrument genuinely originates from the intended analyte rather than from some other component of the sample matrix.
In Indonesian laboratories, Diosmin is widely used in natural product pharmaceutical research and in laboratory work concerned with the characterisation of plant-derived flavonoids. It supports method development and verification activities where a defined reference material is required to interpret instrument output with confidence, particularly in studies of extracts and herbal-based preparations that form a substantial part of the local research landscape.
Laboratory Applications
- Reference standard in natural product analysis — the defined glycosidic structure allows analysts to confirm the identity of a flavonoid peak observed in a plant extract rather than relying on retention behaviour alone.
- Chromatographic method development — the flavone chromophore gives a strong ultraviolet detector response, making the compound a practical marker when establishing separation conditions for flavonoid-containing samples.
- Spectroscopic identity confirmation — the well-characterised aglycone and sugar combination provides a consistent spectral signature that can be compared directly against signals recorded from unknown or partially purified samples.
- Flavonoid biological activity studies — as a test material in chemical biology work, Diosmin allows researchers to examine how a glycosylated flavone behaves in comparison with related aglycone structures.
- Herbal product quality evaluation — the material serves as a comparison substance when verifying that an active compound reported in a herbal-based preparation is genuinely present and not a matrix artefact.
Specifications
- Brand: TCI
- CAS number: 520-27-4
- Catalogue number: D3908
- Category: Chemistry > Chemical Biology > Glycoscience
- Compound class: Natural flavonoid glycoside (flavone linked to a sugar unit)
- Grade: Research reagent quality
- Pack sizes and physical form: please refer to the current TCI catalogue listing for this item
Handling and Storage
Store the container in a cool, dry place, kept tightly closed and protected from light and moisture, in line with the storage instructions printed on the manufacturer's label for this item. Keep the material in its original container wherever possible; if it must be transferred, use clean, dry, chemically compatible glass or suitable plastic vessels that can be sealed and clearly labelled with the compound name, catalogue number, and CAS number. Handle the substance in a well-ventilated area or fume hood, wear a laboratory coat, safety glasses, and appropriate gloves, and avoid generating dust when weighing out portions. Use clean, dry spatulas to prevent contamination that would compromise the material's value as a reference standard, and allow the container to reach ambient temperature before opening so that condensation does not affect the contents. Consult the manufacturer's safety data sheet before first use and follow local institutional rules for chemical waste disposal.
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