TCI
Dansylamide [for Albumin binding assay] TCI D5405
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Description
Dansylamide, with CAS number 1431-39-6, is a chemical compound widely used in scientific research, particularly in pharmacology and pharmaceutical chemistry. It serves as an essential reagent in albumin binding assays, which are critical for studying how drugs interact with plasma proteins. In the laboratory, this compound is used to evaluate the ability of a substance to bind to albumin, a key protein in blood plasma. Understanding this interaction is vital for assessing drug distribution and metabolism within the body.
The compound is valued for its chemical stability and reactivity, making it suitable for a variety of experimental conditions. Its molecular structure allows for specific binding to albumin, ensuring accurate and reliable results. This specificity is crucial in pharmaceutical research, where precise data is necessary for drug development and formulation. The consistency of results obtained with dansylamide makes it a preferred choice for researchers aiming to produce reproducible data.
In Indonesian laboratories, dansylamide is commonly used by researchers and research institutions to support studies on drug-protein interactions. It plays a significant role in the development of new pharmaceuticals and in the analysis of existing drugs. Its application is widespread in both academic and industrial research settings, contributing to the advancement of pharmacological studies in the region.
Laboratory Applications
- Albumin Binding Assays: This item is ideal for assessing how drugs interact with albumin, a critical protein in plasma, allowing researchers to evaluate drug distribution and metabolism.
- Pharmaceutical Development: It supports the development of new drugs by providing insights into their binding behavior with plasma proteins, which is essential for formulation and dosing.
- Drug Interaction Studies: Dansylamide enables the investigation of how different compounds interact with albumin, helping to predict potential drug interactions and side effects.
- Bioavailability Analysis: It is used to study how drugs are absorbed and distributed in the body, offering valuable data for optimizing therapeutic outcomes.
- Research and Development in Biopharmaceuticals: This compound is crucial for developing biopharmaceuticals, where understanding protein binding is essential for efficacy and safety.
Specifications
- Brand: TCI
- CAS Number: 1431-39-6
- Category: Chemistry > Pharmaceutical Development and Drug Discovery Research Reagents > Albumin Binding Agents
- Pack Sizes: Available in various quantities as per standard laboratory supply
- Physical Form: Solid powder
- Storage Note: Store in a cool, dry place away from light
Handling and Storage
Dansylamide should be stored in a cool, dry place, away from direct light to maintain its chemical stability. It is recommended to keep the compound in a sealed container to prevent moisture absorption and contamination. Proper labeling of containers is essential for safe handling and identification. When handling, it is advisable to use appropriate personal protective equipment, such as gloves and safety goggles, to minimize exposure. The compound is generally non-hazardous under normal laboratory conditions, but care should be taken to avoid inhalation or contact with skin. Regular checks of storage conditions ensure the integrity of the material is preserved for reliable experimental results.
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