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Description
2'-Deoxy-2'-fluoroguanosine is a chemical compound widely used in biochemical and pharmacological research. It serves as a key reagent in laboratory settings, playing a crucial role in enzyme studies and biochemical reaction mechanisms. This compound is structurally similar to guanosine, but with a fluorine atom replacing a hydrogen at the 2' position. Its unique structure makes it an essential tool for investigating molecular interactions and enzymatic activity.
The compound is favored for its chemical stability and ability to interact with various proteins and enzymes. It exhibits polar characteristics, allowing it to dissolve in organic solvents such as acetone or ethyl acetate. These properties make it a versatile reagent in both synthetic and analytical applications. Additionally, its capacity to either accelerate or inhibit specific metabolic pathways enhances its utility in research.
In Indonesian laboratories, 2'-Deoxy-2'-fluoroguanosine is commonly used in biomedical, pharmaceutical, and biotechnology research. It is integral to drug development, enzyme activity testing, and studies on protein function. Its role in understanding molecular mechanisms and biochemical pathways makes it a valuable resource for scientists and researchers.
Laboratory Applications
Enzyme Kinetics Studies: This compound is used to investigate enzyme-substrate interactions and reaction rates, providing insights into catalytic mechanisms.
Drug Development Research: It serves as a model compound for studying the effects of fluorinated nucleosides on cellular processes and drug metabolism.
Toxicity Testing: The compound is employed in assays to evaluate the impact of nucleoside analogs on cell viability and metabolic activity.
Molecular Interaction Analysis: Due to its ability to bind with proteins and enzymes, it is used to study molecular recognition and binding affinities.
Biochemical Pathway Modulation: It is utilized to explore how fluorinated nucleosides can influence metabolic pathways and cellular functions.
Specifications
Brand: TCI
CAS Number: 78842-13-4
Category: Life Science > Biochemicals and Reagents > Antibiotics
Pack Sizes: Available in various quantities as per standard laboratory requirements
Physical Form: Solid or powder, depending on the specific formulation
Storage Note: Store in a cool, dry place away from light and moisture
Handling and Storage
This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers made of glass or high-density polyethylene to prevent contamination and degradation. Due to its polar nature, it is important to handle it with proper personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Avoid exposure to incompatible substances, and ensure proper ventilation when working with larger quantities. Always follow standard laboratory safety protocols to minimize risks associated with handling chemical reagents.
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