N-Ethylcarbazole-3-carboxaldehyde TCI E0359

Chemical Identity

Other names: 3-Formyl-N-ethylcarbazole
CAS No.: 7570-45-8
PubChem: CID 82055·SID 87569621
Formula: C15H13NO
Molecular weight: 223.28 g/mol
Purity: >98.0%(GC)
Reference databases: ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 9-ethylcarbazole-3-carbaldehyde
SMILES: CCN1C2=C(C=C(C=C2)C=O)C3=CC=CC=C31
InChIKey: QGJXVBICNCIWEL-UHFFFAOYSA-N
MDL: MDL00004963

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TCI E0359, CAS number 7570-45-8, is N-Ethylcarbazole-3-carboxaldehyde, a carbazole derivative bearing an aldehyde group at the 3-position and an ethyl group on the nitrogen atom. This compound is a highly useful heterocyclic building block because it combines an electron-donating core with a strongly reactive aldehyde functional group. In the laboratory, this material serves as a practical bridge toward a wide range of functional molecules, since the aldehyde can be converted directly into imines, alkenes, alcohols, carboxylic acids, or further heterocyclic systems.

The characteristic that makes this compound a frequent choice is the placement of the aldehyde group at precisely the position most conjugated with the carbazole system, creating an inherent donor-acceptor architecture that gives rise to attractive optical properties. This matters greatly to researchers designing fluorescent dyes and probes. In addition, the reactivity of aromatic aldehydes toward Knoevenagel condensation, Wittig reactions, reductive amination, and Schiff base formation is already very well established procedurally, so researchers can work with standard protocols. The ethyl group on the nitrogen ensures that no N-H proton is present to interfere with reactions.

In Indonesian laboratories, this building block is typically found in university and institutional research groups working on organic synthesis, materials chemistry, and photophysical characterization. It is commonly used in postgraduate research projects, thesis work, and collaborative studies where a reliable carbazole scaffold is needed as a starting point. Research teams developing fluorescent sensors, organic electronic materials, or novel heterocyclic compounds generally keep this reagent available as part of their standard synthetic inventory.

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Schiff base synthesis — the aromatic aldehyde condenses readily with primary amines under well-established conditions, giving access to imine ligands and extended conjugated systems built on the carbazole core.
Knoevenagel condensation — the reactive aldehyde couples with active methylene compounds to produce push-pull alkenes, exploiting the electron-donating carbazole unit to generate strong donor-acceptor character.
Fluorescent dye and probe development — the aldehyde sits at the position most conjugated with the carbazole system, producing the built-in donor-acceptor architecture that underlies attractive optical behaviour in probe design.
Wittig olefination — the aldehyde group undergoes standard ylide chemistry to install alkene linkages, allowing researchers to extend conjugation from the carbazole scaffold using routine published protocols.
Reductive amination and functional group interconversion — the aldehyde can be converted directly into amines, alcohols, or carboxylic acids, making this a flexible entry point toward diverse functional molecules.

Brand	TCI
CAS number	7570-45-8
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes	available in standard TCI research-scale packaging; please confirm the required size when ordering
Physical form	—
Storage	store according to the manufacturer's label instructions

Chemical name: N-Ethylcarbazole-3-carboxaldehyde
Product code: E0359

Store this material in a tightly closed original container, kept in a cool, dry, well-ventilated area away from direct sunlight, moisture, and sources of ignition. Aromatic aldehydes are generally sensitive to prolonged air exposure, so containers should be resealed promptly after use and handled under conditions that limit atmospheric contact where the application requires it. Handle in a fume hood using standard laboratory personal protective equipment, including safety glasses, a laboratory coat, and chemically resistant gloves. Avoid inhalation of dust and contact with skin or eyes. Keep the material separate from strong oxidizing agents and strong bases. Always consult the manufacturer's safety data sheet before use, and follow institutional procedures for chemical waste disposal.

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