9-Fluorenylmethyl Chloroformate [N-Protecting Agent for Peptides Research] TCI F0197

Chemical Identity

Other names: Fmoc-Cl · Chloroformic Acid 9-Fluorenylmethyl Ester · (9H-Fluoren-9-ylmethoxy)carbonyl Chloride
CAS No.: 28920-43-6
PubChem: CID 34367·SID 87569978
Formula: C15H11ClO2
Molecular weight: 258.70 g/mol
Purity: >97.0%(HPLC)(T)
Storage: 0-10°C
Reference databases: ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 9H-fluoren-9-ylmethyl carbonochloridate
SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)Cl
InChIKey: IRXSLJNXXZKURP-UHFFFAOYSA-N
MDL: MDL00001138

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9-Fluorenylmethyl Chloroformate (FmOC-Cl) is a chemical compound widely used as an N-protecting agent in peptide research. It plays a crucial role in the synthesis of peptides by protecting amino groups from unwanted reactions during chemical processes. This compound is essential for the formation of complex peptide chains by enabling controlled coupling of amino acids. Its application in laboratories ensures the stability and accuracy of the resulting peptide structures.

FmOC-Cl is chemically reactive, particularly towards amino groups, making it highly effective in producing fluorenylmethyl esters. This reactivity is a key factor in its popularity among researchers working in chemical biology and peptide chemistry. The compound's ability to selectively protect amino groups while allowing other functional groups to remain active makes it a preferred choice for high-precision applications. Additionally, its stability under certain conditions facilitates long-term storage and use.

In Indonesian laboratories, FmOC-Cl is commonly used in biochemical and pharmacological research. It is particularly relevant for drug development, peptide characterization, and molecular structure studies. Its reliability in peptide synthesis processes ensures consistent results, making it an essential tool for researchers aiming for accuracy and reproducibility.

TCI brochures (PDF)

Protecting Agents 2025-03-25 · p. 9
Fluorenes and Fluorenones 2026-04-15 · p. 3
Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 41

Related TCI products

Peptide Synthesis: FmOC-Cl is ideal for peptide synthesis due to its ability to selectively protect amino groups, ensuring accurate coupling of amino acids.
Biochemical Research: This compound supports biochemical studies by maintaining the integrity of peptide structures during complex reactions.
Drug Development: FmOC-Cl is used in drug development to facilitate the synthesis of bioactive peptides with precise molecular structures.
Molecular Characterization: Its reactivity and selectivity make it suitable for molecular characterization studies involving peptide-based compounds.
Structural Studies: FmOC-Cl enables detailed structural analysis of peptides, aiding in understanding their biological functions and interactions.

Brand	TCI
CAS number	28920-43-6
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Solid
Storage	Store in a cool, dry place away from light and moisture

FmOC-Cl should be stored in a cool, dry environment, away from light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and air. Due to its reactivity, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. Avoid contact with moisture or incompatible substances to prevent unintended reactions. Proper ventilation is essential when working with this compound to ensure a safe laboratory environment. Always follow standard chemical safety protocols to minimize risks during handling and use.

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