• Benzyl Chloroformate (30-35% in Toluene) (CAS 501-53-1) - TCI C0176 - AMI Scientific
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TCI

CAS 501-53-1

Benzyl Chloroformate (30-35% in Toluene) TCI C0176

Benzyl Chloroformate (30-35% in Toluene) TCI C0176
Rp 505.050,00
Rp 505.050,00
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TCI C0176 Benzyl Chloroformate (30–35% in Toluene), CAS 501-53-1, is a widely used acylating reagent for introducing the Cbz (benzyloxycarbonyl) protecting group onto amines. Supplied as a toluene solution in a 25 mL pack, it is convenient to measure and dispense for research-scale organic and peptide synthesis. The resulting carbamates are stable under many reaction conditions yet can be removed by hydrogenolysis, supporting orthogonal protection strategies. Handle it in a fume hood with appropriate protective equipment, keep the container tightly closed, and store it in a cool, dry, well-ventilated area away from ignition sources.

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  • Lezama et al. (2014). Kinetics of the Gas-Phase Elimination Reaction of Benzyl Chloroformate and Neopentyl Chloroformate. International Journal of Chemical Kinetics doi:10.1002/kin.20896
  • Pati et al. (2004). Synthesis of N‐Benzylated Anilines from the Reaction of Anilines and Benzyl Chloroformate.. ChemInform doi:10.1002/chin.200431064
  • Mizuno et al. (2003). Non‐phosgene Synthesis of Benzyl Chloroformate (CbzCl).. ChemInform doi:10.1002/chin.200301081

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