TCI
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Description
TCI G0086 Triacetin is the triester of glycerol with acetic acid, commonly referred to as glyceryl triacetate. Unlike long-chain glycerides that exist as solids at ambient conditions, this compound is a colourless liquid of moderate viscosity because all three of its acyl chains are very short. In the laboratory, Triacetin serves several roles at once: as a building block for organic synthesis that supplies a protected glycerol framework, as a solvent for materials that dissolve poorly in water, and as a plasticising component in research on cellulose acetate and related polymers.
The properties that make Triacetin a frequent choice begin with its good solubility across a wide range of organic solvents, combined with a limited but meaningful solubility in water, which allows it to bridge partially aqueous systems. Being a liquid, the material is easy to pipette and to measure volumetrically without any melting step beforehand. Its three ester groups can be hydrolysed in a controlled manner, either by esterase enzymes or by chemical means, which makes Triacetin a practical model substrate for kinetic studies. Its low vapour pressure also means it does not evaporate quickly over the course of an experiment.
In Indonesia, Triacetin is encountered in laboratories where the same combination of roles is needed: synthetic groups that require a protected glycerol scaffold, analytical and formulation work calling for a solvent outside the purely aqueous range, and polymer research on cellulose acetate and its derivatives. Because it is dispensed volumetrically and does not evaporate rapidly, it fits routine benchtop procedures as well as longer experimental runs without special handling arrangements.
Laboratory Applications
- Organic synthesis building block — supplies a fully acetylated glycerol backbone, so the hydroxyl positions arrive already protected and can be released in a controlled manner later in a sequence.
- Solvent for poorly water-soluble materials — its good miscibility with many organic solvents lets it dissolve substances that resist water, while its limited water solubility helps bridge partially aqueous systems.
- Plasticiser studies on cellulose acetate — used as a plasticising component in polymer research, where its liquid state and low volatility allow it to remain within the matrix during processing and evaluation.
- Model substrate for esterase kinetics — the three ester groups hydrolyse in a controlled way under enzymatic action, giving a reproducible and conveniently measured system for enzyme activity work.
- Controlled chemical hydrolysis experiments — the same ester groups respond to chemical hydrolysis, so the compound serves as a straightforward reference substrate when comparing reaction conditions or catalysts.
Specifications
- Brand: TCI
- CAS number: 102-76-1
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Pack sizes: available in the pack sizes listed for this catalogue item; please refer to the product listing for the options offered
- Physical form: colourless liquid of moderate viscosity
- Storage note: keep in a tightly closed container, protected from moisture, in accordance with the manufacturer's product documentation
Handling and Storage
Store Triacetin in its original tightly closed container, kept upright in a cool, dry and well-ventilated area away from heat sources and from incompatible materials. Glass bottles with chemically resistant closures are suitable, and containers should be resealed immediately after dispensing to limit contact with atmospheric moisture, since the ester groups are subject to hydrolysis. Handle the liquid in a fume hood or other well-ventilated workspace, wearing safety glasses, gloves and a laboratory coat. Transfer volumetrically using clean, dry pipettes or dispensers to avoid introducing water or contaminants, and follow the manufacturer's safety data sheet for the complete handling, spill and disposal procedures applicable at your facility.
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