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Description
n-Octyl Gallate is the linear octyl ester of gallic acid, combining a trihydroxyphenol core with an unbranched eight-carbon alkyl chain. This pairing produces an amphiphilic molecule with a polar head that actively quenches free radicals and a hydrocarbon tail that blends readily into lipid phases. In the laboratory, the compound serves both as a non-heterocyclic building block and as a widely used reference antioxidant, appearing frequently in research on foods, vegetable oils, and formulations that are vulnerable to oxidation during storage.
The property that makes this material such a common choice is its lipophilicity, which is far higher than that of gallic acid itself or of shorter-chain esters. Because of this, the compound concentrates at the oil–water interface, precisely where oxidation reactions typically begin, and it has become a classic illustration in discussions of the polar paradox in antioxidant studies. In addition, the three adjacent aromatic hydroxyl groups allow complexation with metal ions, so the compound also inhibits metal-catalysed oxidation. Its solid form makes accurate weighing of small quantities straightforward when preparing stock solutions.
Indonesian laboratories typically encounter n-Octyl Gallate in food science and edible-oil research groups, where oxidative stability during storage is a recurring concern in a warm, humid climate. It is also used in synthetic chemistry work as a non-heterocyclic building block, and in comparative antioxidant screening where a well-characterised lipophilic reference is required. The solid presentation suits routine gravimetric preparation of stock solutions in university, government, and industrial quality-control settings.
Laboratory Applications
- Antioxidant reference standard — provides a well-characterised lipophilic benchmark against which the radical-quenching performance of new or natural antioxidant candidates can be measured consistently.
- Edible oil and vegetable oil oxidation studies — its strong affinity for lipid phases lets it concentrate where oxidation begins, making it directly relevant to oil stability testing.
- Food science storage research — used to investigate how oxidation progresses in susceptible formulations over time and how effectively a lipophilic antioxidant delays that deterioration.
- Polar paradox investigations — serves as the textbook example for demonstrating how chain length and interfacial partitioning influence antioxidant effectiveness in emulsion and bulk oil systems.
- Non-heterocyclic building block in synthesis — the trihydroxyphenol core and linear alkyl ester give chemists a versatile starting point for constructing related gallate derivatives.
Specifications
- Brand: TCI
- CAS number: 1034-01-1
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Pack sizes: available in standard catalogue research pack sizes; please confirm the size required when ordering
- Physical form: solid, which allows accurate weighing of small quantities for stock solution preparation
- Storage: keep in a tightly closed original container, protected from air, light, and moisture
Handling and Storage
Store n-Octyl Gallate in its original tightly closed container in a cool, dry place away from direct sunlight, moisture, and sources of heat. Because the compound is a phenolic antioxidant, minimising contact with air and light helps preserve its quality over time. Use clean, dry spatulas and glassware when weighing, and reseal the container promptly after each use. Handle the solid in a well-ventilated area or fume hood, wearing standard laboratory personal protective equipment including safety glasses, gloves, and a lab coat. Avoid generating dust, avoid contact with skin and eyes, and wash hands thoroughly after handling. Keep the material separated from strong oxidising agents and consult the supplier safety data sheet before first use.
