TCI H0603 Sodium Hyaluronate from Cockscomb is the sodium salt of hyaluronic acid obtained from rooster comb, the classic natural source of this glycosaminoglycan. Hyaluronic acid is a linear, repeating polysaccharide that occurs naturally in the extracellular matrix, in synovial fluid, and in skin. In the laboratory, this material serves as a standard test substance for glycoscience research, as a substrate in hyaluronidase enzyme assays, and as a starting material for the preparation of biomaterials and cell culture scaffolds. Its reagent-grade purity makes it a dependable reference whenever researchers require a hyaluronate source of clear and documented origin.
The characteristics that make this product a preferred choice begin with its exceptional capacity to bind very large quantities of water and to form thick solutions that behave viscoelastically even at low concentration. The polymer chain carries ionized carboxylate groups, so it behaves as a polyanion and readily interacts with positively charged polymers to form polyelectrolyte complexes. The carboxyl and hydroxyl groups along the chain additionally provide well-defined points for chemical modification, allowing the hyaluronate to be grafted with other functional groups for tailored research purposes. Together these properties give consistent, reproducible behaviour across rheological, enzymatic, and formulation work.
In Indonesian laboratories, this grade is typically used in university and institutional research groups working on glycoscience, enzymology, and biomaterials development, as well as in formulation and applied research settings where a hyaluronate of traceable natural origin is required. It suits method development, comparative testing against in-house or alternative materials, and preparation of reference solutions, where a documented catalogue material removes uncertainty about the source of the polysaccharide under study.
- Glycoscience research reference material — provides a hyaluronate of clearly documented natural origin, so structural and analytical studies rest on a consistent, traceable starting polysaccharide.
- Hyaluronidase enzyme assays — acts as the substrate whose enzymatic depolymerisation is followed, with reagent-grade purity limiting interference from extraneous material during activity measurement.
- Biomaterial preparation — serves as the base polysaccharide for research biomaterials, since carboxyl and hydroxyl groups allow grafting of other functional groups onto the chain.
- Cell culture scaffold work — supplies a matrix-derived polysaccharide for scaffold preparation, reflecting the natural role of hyaluronic acid within the extracellular matrix.
- Polyelectrolyte complex studies — the ionized carboxylate groups make it a polyanion that readily associates with positively charged polymers, supporting complexation and interaction research.
| Brand | TCI |
|---|---|
| CAS number | 9067-32-7 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > Glycoscience |
| Pack sizes | available in the standard catalogue pack sizes listed for this item; confirm the exact size when ordering |
| Physical form | — |
| Storage | store according to the conditions stated on the product label and Certificate of Analysis |
- Source: sodium salt of hyaluronic acid derived from cockscomb
Store the container according to the storage conditions printed on the product label and accompanying documentation, keeping it tightly closed in a cool, dry place and protected from moisture, since the material binds water strongly and can take up humidity from the surrounding air. Keep it in its original container or in a clean, dry, well-sealed vessel, and allow refrigerated stock to reach room temperature before opening to avoid condensation. Handle with clean, dry spatulas to prevent contamination, weigh in a low-draught area because the material is light and readily disperses, and observe general laboratory practice: wear a lab coat, gloves, and eye protection, avoid dust generation and inhalation, and consult the Safety Data Sheet before use and before disposal.
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