TCI H0837 2-Hexadecyloctadecanoic Acid is a high molecular weight branched fatty acid composed of an octadecanoic acid chain carrying a hexadecyl substituent at the alpha position. Long branched structures of this kind are known as Guerbet-type acids and occupy a distinct niche in lipid research, amphiphilic materials, and formulation work. In the laboratory, this compound serves as an exceptionally strong hydrophobic component, as a structural analogue of branched mycolic acids, and as a starting material for preparing long-chain esters, amides, and salts whose physical behaviour differs markedly from that of ordinary linear fatty acids.
The characteristic that drives its selection is the branching at the alpha position, which disrupts the regular packing of the chains. As a result, this compound and its derivatives tend to show a lower crystallisation tendency and better solubility in nonpolar organic solvents than straight-chain fatty acids of comparable carbon number. This property is highly valued when researchers design lipids for formulations that must remain liquid or amorphous, for example in studies of lipid nanoparticles, delivery systems, inks, specialty lubricants, and nonionic surfactants. The carboxylic acid group provides a reactive handle for further chemical modification.
In Indonesian laboratories, this building block is typically used in academic and industrial research groups working on lipid chemistry, surfactant development, and specialty formulation. It is handled on a small synthetic scale for the preparation of derivatives, for comparative studies against linear fatty acid references, and for the evaluation of hydrophobic modifiers in material systems. Its role is that of a well-defined, research-grade starting material rather than a bulk process chemical.
- Synthesis of long-chain esters and amides, where the branched acid contributes a bulky hydrophobic tail that lowers crystallinity and keeps the resulting derivative flowable at ambient conditions.
- Lipid nanoparticle and delivery system research, where a Guerbet-type acid is incorporated to maintain an amorphous or liquid core instead of the ordered packing typical of linear fatty acid analogues.
- Structural analogue studies of branched mycolic acids, where the alpha-branched octadecanoic framework provides a simplified, commercially defined model compound for comparative investigations.
- Nonionic and specialty surfactant development, where the carboxylic acid group serves as the reactive handle and the branched chain supplies the strongly hydrophobic segment of the amphiphile.
- Formulation of inks and specialty lubricants, where improved solubility in nonpolar organic solvents and reduced crystallisation tendency help maintain homogeneity across the working temperature range.
| Brand | TCI |
|---|---|
| CAS number | 89547-15-9 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | available in standard TCI research quantities; please confirm the packaging option when ordering |
| Physical form | — |
| Storage | keep in the tightly closed original container, in a cool and dry place away from light |
- Chemical class: alpha-branched (Guerbet-type) long-chain fatty acid
Store the container tightly closed in a cool, dry, and well-ventilated area, protected from direct sunlight and away from strong oxidising agents and strong bases. The original supplier container is the preferred storage vessel; if transfer is required, use clean glass containers with chemically resistant closures and label them clearly. Handle in a fume hood or a well-ventilated workspace, and wear safety glasses, gloves, and a laboratory coat. Avoid generating dust or aerosols, avoid contact with skin and eyes, and keep the container closed when not in active use to prevent moisture uptake and contamination. Always consult the manufacturer safety data sheet before first use and follow institutional waste disposal procedures.
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