Heptaethylene Glycol Monomethyl Ether TCI H1046

Heptaethylene Glycol Monomethyl Ether (HEGME), also known as TCI H1046 with CAS number 4437-01-8, is a chemical compound widely used in laboratory settings, particularly in the fields of chemical biology and PEGylation. This compound is a polyether derivative with a long chain of ethylene glycol units and a methyl group at one end. Its unique molecular structure allows it to participate in various chemical reactions, making it an essential reagent for researchers working on molecular modification and drug delivery systems. HEGME is commonly found in laboratories that focus on biomolecular engineering and advanced chemical synthesis.

HEGME is valued for its high reactivity and ability to form stable chemical bonds with a variety of molecules. It exhibits good solubility in organic solvents such as ethyl acetate and acetone, which makes it suitable for use in reactions requiring controlled environments. Its high boiling point ensures stability under elevated temperatures, while its moderate sensitivity to moisture and oxidation requires careful handling. These properties make HEGME a preferred choice for applications that demand both reactivity and chemical stability.

In Indonesian laboratories, HEGME is frequently used in research related to protein modification, biomedical applications, and pharmaceutical development. Its availability and reliability make it a staple in academic and industrial research settings. The compound is also used in the development of drug delivery systems and in the synthesis of bioactive molecules. Its safety profile, with no toxicity at normal dosages, further supports its widespread use in controlled laboratory environments.

• PEGylation Research - HEGME is ideal for PEGylation due to its ability to form stable covalent bonds with proteins and other biomolecules, enhancing solubility and reducing immunogenicity.
• Drug Delivery Systems - Its high solubility and reactivity make it suitable for modifying drug molecules to improve their bioavailability and targeting efficiency.
• Protein Modification Studies - HEGME is used to alter protein structures for enhanced stability and functionality in biotechnological applications.
• Biomedical Material Development - Its chemical stability and reactivity support the creation of advanced biomaterials for medical applications.
• Organic Synthesis Reactions - HEGME's solubility in organic solvents and reactivity make it a valuable reagent in complex chemical synthesis processes.

HEGME should be stored in a cool, dry environment to prevent degradation due to moisture and oxidation. It is recommended to use sealed containers made of glass or high-density polyethylene to maintain its chemical integrity. Avoid exposure to direct sunlight and ensure proper ventilation in the storage area. Due to its reactivity, it should be handled with care using appropriate personal protective equipment. Regular monitoring of storage conditions is essential to maintain the compound's stability and effectiveness in laboratory applications.

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