Nonaethylene Glycol Monomethyl Ether TCI N0699

Chemical Identity

CAS No.: 6048-68-6
PubChem: CID 11339376·SID 87574008
Formula: C19H40O10
Molecular weight: 428.5 g/mol
Purity: >90.0%(GC)
Reference databases: ChEBI·ChemSpider

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
SMILES: COCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChIKey: VVHAVLIDQNWEKF-UHFFFAOYSA-N

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Nonaethylene Glycol Monomethyl Ether from TCI (product code N0699, CAS 6048-68-6) is an oligoethylene glycol made up of nine ethylene oxide units. A methoxy group caps one end of the chain, and the other end carries a free hydroxyl group. Because the chain has a single, well-defined length, this material is different from conventional polymeric PEG, which comes as a mixture of molecular weights. In the laboratory it serves as a building block for linkers, hydrophilic spacers, and monodisperse PEG derivatives whose structures can be controlled precisely.

Its main advantage is its monodisperse structure. Synthetic products built from it are easier to characterise by NMR and mass spectrometry, and results stay consistent from one batch to the next. Only one end of the molecule is reactive, so it can be functionalised selectively, for example by converting it into a tosylate, halide, amine, or carboxylic acid, with no risk of crosslinking. The ethylene oxide chain also makes target molecules more water-soluble and more flexible, two properties that are in high demand in medicinal chemistry and biotechnology.

In Indonesia, this material suits university research laboratories, pharmaceutical research centres, and research groups working in organic synthesis, medicinal chemistry, and bioconjugation. Researchers use it when they need a hydrophilic spacer of exact length, when they are building defined PEG-based linkers for new molecular designs, or when they need reproducible results for publications and development projects. As a TCI building block, it gives Indonesian laboratories a well-characterised starting material for multistep synthetic work.

TCI brochures (PDF)

PEGylation Reagents 2025-02-18 · p. 1
Bioconjugation Reagents 2026-07-07 · p. 6
Biomaterials Research Reagents 2025-02-19 · p. 7
Reagents for Biological Research 2025-03-11 · p. 32

Related TCI products

Linker synthesis: the single reactive hydroxyl end allows stepwise attachment to other molecules, producing linkers of defined length without the crosslinking that difunctional glycols can cause.
Hydrophilic spacer design: the nine-unit ethylene oxide chain adds water solubility and flexibility between functional groups, which helps in medicinal chemistry and biotechnology research.
Preparation of monodisperse PEG derivatives: because the chain length is single and defined, the derivatives made from it have exact structures that are easier to purify and characterise than those made from polydisperse PEG.
Selective end-group functionalisation: the free hydroxyl can be turned into a tosylate, halide, amine, or carboxylic acid, giving versatile intermediates for further coupling reactions.
Analytical and reproducibility-focused synthesis: its monodisperse nature makes products easier to analyse by NMR and mass spectrometry, so results stay consistent from batch to batch.

Brand	TCI (product code N0699)
CAS number	6048-68-6
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	see the pack size options listed on the product page
Physical form	see the TCI product specification and certificate of analysis
Storage	follow the conditions stated on the TCI label and Safety Data Sheet

Store Nonaethylene Glycol Monomethyl Ether in its original tightly closed container, in a cool, dry, well-ventilated place away from direct sunlight, heat sources, and strong oxidising agents. Glycol ethers can absorb moisture from the air, so keep the container sealed when not in use and reseal it promptly after dispensing. Always check the TCI label and Safety Data Sheet for the specific recommended storage conditions. Handle the material under good laboratory practice: wear safety glasses, chemical-resistant gloves, and a lab coat, and work in a fume hood or well-ventilated area. Avoid contact with skin and eyes, and avoid breathing vapours. Use clean, dry glassware and tools to prevent contamination, label secondary containers clearly, and dispose of waste according to institutional and local regulations.

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