8-Hydroxyquinoline N-Oxide TCI H1272

Description

8-Hydroxyquinoline N-Oxide, with CAS number 1127-45-3, is a heterocyclic chemical compound that is an oxidized derivative of 8-hydroxyquinoline. In the laboratory, this compound plays an important role as a building block or synthesis raw material, that is, an initial molecular unit used to construct more complex compounds. In both organic and inorganic chemistry laboratories, this material is used to assemble ligands, form metal complexes, and serve as an intermediate in the preparation of pharmaceutical compounds and functional materials. The presence of the N-oxide group provides distinctive reactivity not possessed by the parent compound, thereby opening new synthetic pathways such as oxidation reactions, substitution reactions, and the formation of advanced heterocyclic structures. For researchers and analysts, this material is the choice when a stable and versatile heterocyclic framework is required.

The main advantage of 8-Hydroxyquinoline N-Oxide lies in its N-oxide group, which is polar and electron-rich, making the compound able to interact readily with metal ions and other functional groups. The aromatic quinoline core structure makes the compound relatively stable toward heat and many reaction conditions. This combination of electron-rich functionality and aromatic stability means the compound behaves predictably across a wide range of transformations, from ligand design to coordination chemistry. Its balanced reactivity profile makes it convenient to handle under standard organic synthesis conditions, reducing the need for specialized equipment or unusual procedures. These properties explain why it is frequently selected when chemists need a dependable heterocyclic scaffold that can be further functionalized.

In Indonesian laboratories, this product is typically used in academic and industrial research settings focused on organic synthesis, coordination chemistry, and materials science. It is commonly applied when researchers design new ligands for metal complexes, investigate catalytic systems, or prepare intermediates for pharmaceutical and functional material development. Analytical chemists and laboratory analysts also keep it on hand as a versatile heterocyclic building block for exploratory synthesis and method development. Because the Indonesian version of the product page carries the same facts, the role and applications described here apply equally in local research groups, where the compound supports both routine synthesis work and advanced studies in heterocyclic chemistry.

Laboratory Applications

• Ligand synthesis: the electron-rich N-oxide and quinoline nitrogen sites coordinate metal ions easily, making this building block ideal for assembling new ligands in coordination chemistry studies.
• Metal complex formation: its polar, electron-rich N-oxide group interacts readily with metal ions, so researchers can use it to construct stable metal complexes for catalysis and materials research.
• Pharmaceutical intermediate preparation: as a stable heterocyclic unit, it serves as a reliable intermediate for building pharmaceutical compounds and functional materials through multi-step organic synthesis.
• Advanced heterocyclic construction: the distinctive reactivity of the N-oxide group opens new synthetic pathways, including oxidation and substitution reactions that lead to advanced heterocyclic structures.
• Synthetic method development: organic and inorganic chemistry laboratories use this versatile building block to explore new reactions, from oxidation to substitution, and to develop reproducible synthetic routes.

Specifications

• Brand: TCI (product code H1272)
• CAS number: 1127-45-3
• Product name: 8-Hydroxyquinoline N-Oxide
• Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
• Pack sizes: as offered in the standard TCI catalog for this product
• Physical form and storage: as stated on the TCI product label and certificate of analysis supplied with the shipment

Handling and Storage

Store the product in a cool, dry place away from direct sunlight, heat sources, and moisture, preferably in its original tightly sealed container. Keep the container closed when not in use to prevent contamination and moisture uptake. Use suitable laboratory containers, such as clean glassware made of compatible materials, when transferring or dispensing the compound. Wear appropriate personal protective equipment, including gloves, safety goggles, and a laboratory coat, and work in a well-ventilated area or fume hood. Avoid inhalation of dust and contact with skin or eyes, and follow standard laboratory hygiene and waste disposal procedures.

*Asumsi: ukuran kemasan, bentuk fisik, dan suhu penyimpanan spesifik tidak tercantum pada data referensi, sehingga sengaja tidak dicantumkan angka teknis apa pun dan merujuk pada label/certificate of analysis produk TCI.*