Methacroylcholine Chloride (ca 80% in Water) (stabilized with MEHQ) TCI M0918

Chemical Identity

CAS No.: 5039-78-1
PubChem: CID 78738·SID 87572905
Formula: C9H18ClNO2
Molecular weight: 207.70 g/mol
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium chloride
SMILES: CC(=C)C(=O)OCC[N+](C)(C)C.[Cl-]
InChIKey: RRHXZLALVWBDKH-UHFFFAOYSA-M

Rp 662.550,00

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Berat 25g 500g

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TCI M0918 Methacroylcholine Chloride (ca 80% in Water), CAS number 5039-78-1, is a positively charged methacrylate monomer that combines a polymerizable methacryloyl group with a choline-derived quaternary ammonium group within a single molecule. The material is supplied as an approximately 80% aqueous solution stabilized with MEHQ, which acts as an inhibitor against premature polymerization. In the laboratory, its role is to serve as a building block for cationic polyelectrolytes, responsive hydrogels, and charge-modified surfaces that cannot be obtained from ordinary neutral methacrylate monomers. The presence of a permanent charge makes it a primary choice in biomedical materials research.

The characteristic that makes this monomer widely selected is the permanent cationic charge on the quaternary nitrogen, which does not depend on the pH of the medium, so the resulting polymer remains charged across physiological conditions as well as moderately acidic and basic ranges. Its methacryloyl group is readily incorporated into free radical polymerization, including controlled techniques such as RAFT and ATRP, and it can be copolymerized with acrylamide or other methacrylate monomers to tune the hydrophilic-cationic balance. The aqueous solution form simplifies dosing and direct transfer into water-based reaction systems without an additional dissolution step.

In Indonesian laboratories, this monomer is typically used in university and institutional research groups working on drug delivery systems, polymer chemistry, and biomedical materials. It appears in synthesis work where charged polymer carriers, antibacterial coatings, or ion-exchange matrices are prepared on a bench scale. Because it arrives as a stabilized aqueous solution, it fits well into laboratories that run water-based radical polymerization and want to avoid handling a moisture-sensitive solid monomer.

TCI brochures (PDF)

Drug Delivery System (DDS) Research Reagents 2025-01-29 · p. 2
Quaternary Ammonium Salts 2025-11-10 · p. 4
Biomaterials Research Reagents 2025-02-19 · p. 10
Monomers 2025-05-28 · p. 6

Related TCI products

Drug Delivery Systems (DDS) research: the permanent cationic charge allows the resulting polymer to form electrostatic complexes with anionic payloads, which is the mechanism most carrier studies in this category depend on.
Cationic hydrogel synthesis: the methacryloyl group crosslinks readily under free radical conditions, producing water-swollen networks whose charge density can be set directly by the monomer feed ratio.
Controlled radical polymerization studies: the monomer participates in RAFT and ATRP systems, letting researchers prepare cationic blocks with defined architecture rather than uncontrolled statistical chains.
Charge-modified surface preparation: grafting this monomer onto substrates produces surfaces with pH-independent positive charge, useful where neutral methacrylate coatings cannot provide the required interfacial behaviour.
Copolymer formulation work: pairing it with acrylamide or other methacrylates lets laboratories tune the hydrophilic-cationic balance of the product across a broad compositional range in aqueous media.

Brand	TCI
CAS number	5039-78-1
Molecular formula	—
Purity	—
Category	Chemistry > Pharmaceutical Development and Drug Discovery Research Reagents > Drug Delivery Systems (DDS)
Pack sizes	please refer to the packaging options listed on this product page
Physical form	approximately 80% solution in water, stabilized with MEHQ
Storage	keep the stabilizer effective by storing under the conditions stated on the manufacturer label

Catalog number: M0918

Store the container tightly closed in its original packaging, in a cool and well-ventilated area away from heat sources, direct sunlight, and ignition sources, following the storage conditions printed on the manufacturer label. The MEHQ stabilizer must not be removed or allowed to deplete, since it prevents premature polymerization during storage; avoid prolonged warming of the solution for the same reason. Use the original supplier container or a compatible, clearly labelled closed vessel for any transfer. Handle in a fume hood with nitrile gloves, safety goggles, and a laboratory coat, avoid contact with skin and eyes, and consult the manufacturer safety data sheet before first use. Keep a record of the opening date and inspect the solution for any change in appearance or viscosity before each use.

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