Methyltetrazine-PEG4-NHS Ester is a chemical compound widely used in chemical biology, particularly in conjugation chemistry and click chemistry applications. This reagent plays a crucial role in laboratories by enabling the efficient and specific formation of covalent bonds between biomolecules. Its unique structure allows it to act as a versatile tool for molecular conjugation, making it indispensable in various research areas. The compound is commonly utilized in the development of bioconjugates, including proteins, antibodies, and nucleic acids, where precise and rapid chemical reactions are essential.
One of the key properties that make Methyltetrazine-PEG4-NHS Ester a preferred choice is its ability to selectively react with tetrazole-containing molecules. This selectivity ensures high specificity and efficiency in chemical reactions, reducing the likelihood of side reactions and improving the overall success rate of conjugation processes. Additionally, the PEG chain enhances the solubility and stability of the compound in different solvents, making it suitable for a wide range of experimental conditions. These characteristics contribute to its popularity in advanced biochemical research and drug development.
In Indonesian laboratories, Methyltetrazine-PEG4-NHS Ester is extensively used in biomedical and pharmaceutical research. It supports the development of targeted therapies, diagnostic tools, and molecular imaging agents. Its role in facilitating rapid and reliable conjugation reactions makes it a valuable asset in both academic and industrial research settings. The compound’s versatility and effectiveness have made it a standard reagent in many laboratory workflows across Indonesia.
TCI brochures (PDF)
- trans-Cyclooctenes and Tetrazines for Metal Free Conjugation 2026-03-19 · p. 6
- Click Chemistry 2026-09-08 · p. 18
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- Bioconjugation Research: This compound is ideal for creating stable and specific molecular linkages between biomolecules, enabling the development of advanced therapeutic and diagnostic agents.
- Click Chemistry Applications: Its rapid and efficient reaction with tetrazole groups makes it a preferred reagent for click chemistry experiments, enhancing reaction speed and yield.
- Protein and Antibody Conjugation: The NHS ester functionality allows for the covalent attachment of proteins and antibodies, making it suitable for immunological and therapeutic applications.
- Nucleic Acid Modifications: It supports the conjugation of DNA and RNA molecules, facilitating the development of molecular tools for genetic research and biotechnology.
- Molecular Imaging Studies: The hydrophilic PEG chain enhances the solubility and stability of conjugates, making it useful in imaging and drug delivery applications.
| Brand | TCI |
|---|---|
| CAS number | 1802907-92-1 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > Conjugation Chemistry/Click Chemistry |
| Pack sizes | Available in various quantities as per supplier specifications |
| Physical form | Solid or powder, depending on the formulation |
| Storage | Store at 2–8°C in a dry, cool place away from light |
Methyltetrazine-PEG4-NHS Ester should be stored at 2–8°C in a dry, cool environment to maintain its chemical stability and activity. It is recommended to use airtight containers to prevent moisture absorption, which could affect its performance. The compound should be kept away from direct sunlight and sources of heat to avoid degradation. In laboratory settings, it is important to handle the material with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safe handling. Due to its chemical nature, it should be stored separately from incompatible substances to prevent any potential reactions. Proper labeling and storage conditions are essential to maintain the integrity and effectiveness of the compound in research applications.
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Product Categories
- Chemical BiologyConjugation Chemistry/Click ChemistryCopper-free Click Reaction Reagents
- Chemical BiologyLinkers and CrosslinkersHeterobifunctional Cross-Linkers
- Chemical BiologyBioconjugationCopper-free Click Reaction Reagents
- Chemical BiologyBioconjugationHeterobifunctional Cross-Linkers
- Chemical BiologyBioconjugationPEGylation Reagents and PEG Spacers
- Pharmaceutical Development and Drug Discovery Research ReagentsLinkers and CrosslinkersHeterobifunctional Cross-Linkers
- Biochemicals and ReagentsBioconjugationCopper-free Click Reaction Reagents
- Biochemicals and ReagentsBioconjugationHeterobifunctional Cross-Linkers
- Biochemicals and ReagentsBioconjugationPEGylation Reagents and PEG Spacers
- Pharmaceutical Development and Drug Discovery ResearchBioconjugationCopper-free Click Reaction Reagents
- Pharmaceutical Development and Drug Discovery ResearchBioconjugationHeterobifunctional Cross-Linkers
- Pharmaceutical Development and Drug Discovery ResearchBioconjugationPEGylation Reagents and PEG Spacers
- Pharmaceutical Development and Drug Discovery ResearchLinkers and CrosslinkersHeterobifunctional Cross-Linkers
- Pharmaceutical Development and Drug Discovery ResearchConjugation Chemistry/Click ChemistryCopper-free Click Reaction Reagents
