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TCI

CAS 132-66-1

N-(1-Naphthyl)phthalamic Acid TCI N0067

N-(1-Naphthyl)phthalamic Acid TCI N0067

Chemical Identity

CAS No.
132-66-1
PubChem
CID 8594·SID 87573463
Formula
C18H13NO3
Molecular weight
291.3 g/mol
Purity
>99.0%(HPLC)(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-(naphthalen-1-ylcarbamoyl)benzoic acid
SMILES
C1=CC=C2C(=C1)C=CC=C2NC(=O)C3=CC=CC=C3C(=O)O
InChIKey
JXTHEWSKYLZVJC-UHFFFAOYSA-N
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TCI N0067 N-(1-Naphthyl)phthalamic Acid is an organic compound derived from phthalamic acid, carrying a naphthyl group on its amide nitrogen. The material is widely recognised among plant physiology researchers for its ability to interact with the auxin transport system, which is why it is frequently adopted as a tool for studying the movement of growth hormones through plant tissues. In the laboratory it serves a dual role: as a research reagent in its own right, and as a synthetic starting material in the preparation of more complex aromatic amide derivatives. The TCI presentation is supplied in pack sizes that are practical for experimental-scale work.

The characteristics that lead researchers to select this material stem from its structure, which combines a hydrophobic naphthalene ring system with a free carboxylic acid group and an amide linkage. This combination gives the compound a distinctive solubility profile: relatively low in neutral water, but increasing under basic conditions because the carboxylic acid group becomes deprotonated. Polar organic solvents such as dimethyl sulfoxide and acetone are therefore the usual choices for preparing stock solutions. The crystalline solid form is a further practical advantage, since it allows accurate weighing and offers better long-term storage stability than a liquid preparation.

In Indonesian laboratories, this compound is typically encountered in university plant physiology and agricultural science programmes, in agronomy and horticulture research groups, and in synthetic organic chemistry laboratories working on aromatic amide chemistry. Research institutes investigating plant growth and development also draw on it for mechanistic studies of hormone transport. Its supply in experiment-scale packs suits the working pattern of academic and institutional laboratories, where quantities are consumed steadily across multiple trials rather than in bulk.

TCI brochures (PDF)

  • Auxin transport studies in plant tissues: the compound's established interaction with the auxin transport system makes it a direct experimental tool for tracing how growth hormones move through plant structures.
  • Plant physiology teaching and research experiments: its well-documented behaviour as a research reagent allows reproducible demonstrations and investigations of growth hormone regulation in university laboratory settings.
  • Synthesis of complex aromatic amide derivatives: the free carboxylic acid group and existing amide linkage provide reactive handles for building more elaborate aromatic amide structures from a defined starting material.
  • Preparation of stock solutions for bioassay work: solubility in polar organic solvents such as dimethyl sulfoxide and acetone permits convenient preparation of concentrated solutions for subsequent dilution into assay systems.
  • pH-dependent solubility investigations: the carboxylic acid group deprotonates under basic conditions, making the material useful where solubility behaviour across different pH environments needs to be examined or exploited.

Brand TCI (Tokyo Chemical Industry)
CAS number 132-66-1
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes supplied in pack sizes practical for experimental-scale laboratory work
Physical form crystalline solid, suitable for accurate weighing and stable long-term storage
Storage —
  • Chemical name: N-(1-Naphthyl)phthalamic Acid

Store the material in a tightly closed original container, kept dry and protected from moisture and direct sunlight. Its crystalline solid form makes it more stable in long-term storage than a liquid preparation, provided the container is properly sealed after each use. Handle the compound in a well-ventilated area or fume hood, using standard laboratory personal protective equipment including gloves, safety glasses and a laboratory coat, and avoid generating or inhaling dust during weighing. Prepared stock solutions in dimethyl sulfoxide or acetone should be stored in clearly labelled, solvent-compatible containers with secure closures. Always consult the manufacturer's safety data sheet before use and follow local institutional waste disposal procedures.

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