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TCI

CAS 6054-98-4

Olsalazine Sodium TCI O0517

Olsalazine Sodium TCI O0517

Chemical Identity

CAS No.
6054-98-4
PubChem
CID 135413505·SID 354335800
Formula
C14H8N2Na2O6
Molecular weight
346.20 g/mol
Purity
>98.0%(HPLC)
Reference databases
ChEBI·ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
disodium;2-carboxy-4-[(3-carboxy-4-oxidophenyl)diazenyl]phenolate
SMILES
C1=CC(=C(C=C1N=NC2=CC(=C(C=C2)[O-])C(=O)O)C(=O)O)[O-].[Na+].[Na+]
InChIKey
ZJEFYLVGGFISGT-UHFFFAOYSA-L
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Olsalazine Sodium (TCI O0517, CAS 6054-98-4) is a chemical compound widely used in pharmaceutical research and drug development. It plays a crucial role in laboratory settings where the study of drug delivery systems (DDS) is essential. This compound is specifically utilized to investigate how active pharmaceutical ingredients reach their intended targets within the body. Its application extends to the development of treatments for inflammatory bowel diseases, such as ulcerative colitis and Crohn’s disease. As a key reagent in the field of pharmaceutical development, it supports the creation of targeted therapies with improved efficacy and reduced side effects.

One of the main reasons Olsalazine Sodium is preferred in laboratory research is its chemical stability under controlled conditions. It is capable of hydrolyzing into 5-aminosalicylic acid and 2-(4-aminosalicylic acid) within the body, making it an ideal compound for studying drug metabolism and pharmacokinetics. Its predictable behavior and consistent performance make it a reliable choice for researchers aiming to understand the mechanisms of drug action. Additionally, its availability in high-quality reagent form ensures accuracy and reproducibility in experimental results.

In Indonesian laboratories, Olsalazine Sodium is commonly used in drug discovery and development projects, particularly those focused on gastrointestinal disorders. It is also integral to pharmacokinetic studies and research into the effectiveness of new therapeutic agents. Due to its specific chemical properties, it is a favored material in academic and research institutions across Indonesia, supporting both basic and applied research in the pharmaceutical sciences.

  • Drug Development Research: Olsalazine Sodium is used to study the pharmacokinetics and metabolism of active pharmaceutical ingredients, aiding in the design of more effective drug delivery systems.
  • Inflammatory Bowel Disease Studies: This compound is essential for researching treatments for conditions like ulcerative colitis and Crohn’s disease, as it helps understand how drugs target inflamed intestinal tissues.
  • Pharmacokinetic Analysis: Its ability to break down into known metabolites makes it ideal for analyzing drug absorption, distribution, and elimination in experimental models.
  • Drug Delivery System Optimization: Researchers use it to evaluate the efficiency of various drug delivery mechanisms, ensuring that therapeutic agents reach their intended sites of action.
  • Academic and Industrial Research: It is widely adopted in both academic and industrial settings for its reliability and consistency in experimental outcomes.

Brand TCI
CAS number 6054-98-4
Molecular formula —
Purity —
Category Chemistry > Pharmaceutical Development and Drug Discovery Research Reagents > Drug Delivery Systems (DDS)
Pack sizes Available in various quantities as per standard reagent packaging
Physical form Solid powder
Storage Store in a cool, dry place away from light and moisture

Olsalazine Sodium should be stored in a cool, dry environment, away from direct sunlight and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its potential reactivity with moisture, it is important to handle the compound in a controlled laboratory setting, using appropriate personal protective equipment such as gloves and safety goggles. Proper labeling of storage containers is essential to ensure safe handling and prevent accidental exposure. Regular monitoring of storage conditions ensures the compound remains in optimal condition for research use. Always follow standard laboratory safety protocols when working with this reagent.

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