Azathioprine TCI A2069

Chemical Identity

CAS No.: 446-86-6
PubChem: CID 2265·SID 87559964
Formula: C9H7N7O2S
Molecular weight: 277.27 g/mol
Purity: >98.0%(HPLC)(T)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
InChIKey: LMEKQMALGUDUQG-UHFFFAOYSA-N

Rp 4.716.600,00

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Azathioprine is a chemical compound widely used in chemical and pharmacological experiments. It is a key component in the synthesis of complex molecules and plays an essential role in laboratory research. As a heterocyclic building block, it provides a versatile foundation for the development of bioactive compounds, including immunosuppressant drugs. Its unique molecular structure, consisting of a pyrimidine ring and a sulfonamide group, makes it highly relevant in the study of pharmaceutical compounds. Azathioprine is a fundamental material for researchers aiming to explore new synthetic pathways and biological activities.

Azathioprine is valued for its chemical stability under controlled conditions, although it is sensitive to UV light and oxidation. Its heterocyclic nature allows it to react readily with various chemical reagents, enabling the formation of new compounds through substitution or ring-opening reactions. These properties make it an ideal choice for organic synthesis and drug development. Its reactivity and structural versatility support its use in a wide range of chemical and biological applications, making it a preferred material in modern laboratory settings.

In Indonesian laboratories, Azathioprine is extensively used in pharmaceutical, organic chemistry, and biochemical research. It is a critical reagent in the development of new drugs, particularly in immunology and autoimmune disease studies. Its availability and reliability make it a valuable tool for academic and industrial research, contributing to the advancement of medicinal science and therapeutic innovation.

Advantages (TCI brochure)

Prodrug of 6-mercaptopurine (6-MP), inhibits synthesis of purine ribonucleotides and DNA/RNA

TCI brochures (PDF)

Immunosuppressants and Immunostimulants for Research and Experimental Use 2024-09-26 · p. 1
Pharmacologically Active Metabolites 2025-07-22 · p. 2
Biofilm Research Reagents 2024-06-21 · p. 1
Anti-Rheumatoid Arthritis Ingredients 2025-01-29 · p. 1
Immune System, Inflammation, Allergy Research Reagents 2025-05-26 · p. 2
Immunology Research Reagents 2026-06-03 · p. 7

Related TCI products

Pharmaceutical research utilizes Azathioprine for the synthesis of immunosuppressant drugs due to its structural compatibility with bioactive compounds.
Organic chemistry experiments benefit from its reactivity, allowing the creation of new molecular structures through substitution and ring-opening reactions.
Biochemical studies employ Azathioprine to investigate its interactions with biological systems and its potential therapeutic applications.
Drug development programs use it as a building block for the design of novel compounds with improved pharmacological profiles.
Immunology research leverages its properties to study its effects on immune responses and its role in autoimmune disease treatment.

Brand	TCI
CAS number	446-86-6
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	Solid powder
Storage	Store in a cool, dry place away from light and moisture

Azathioprine should be stored in a cool, dry environment, away from direct sunlight and sources of moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to air and potential oxidation. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. Due to its sensitivity to UV light, it is advisable to keep it in a dark storage cabinet or under a light-protective cover. Proper labeling and storage conditions are essential to ensure the integrity and safety of the compound during handling and experimentation.

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