1-Phenyl-3-(2,4,6-trimethylphenyl)-2-pyrazoline TCI P1951

1-Phenyl-3-(2,4,6-trimethylphenyl)-2-pyrazoline is a heterocyclic compound from the 2-pyrazoline class. Its core is a five-membered ring that contains two adjacent nitrogen atoms. A phenyl group is attached to the nitrogen at position 1, and a mesityl (2,4,6-trimethylphenyl) group is attached to the carbon at position 3. In the laboratory, it is used as a heterocyclic building block for making more advanced derivatives. It is also studied for its photophysical properties, because 1,3-diaryl-2-pyrazolines are known to fluoresce.

Researchers choose this compound because its 1,3-diaryl-2-pyrazoline framework has a conjugated system linking the ring nitrogen atoms and the aromatic rings. This conjugation often produces fluorescence emission and charge-transport behaviour, which makes the scaffold interesting for optoelectronic materials. The bulky mesityl group adds steric hindrance around the ring. That hindrance can affect molecular planarity, intermolecular interactions and emission characteristics, so the compound is useful for structure–property relationship studies. The pyrazoline ring can also be oxidised to the corresponding pyrazole or modified further, which gives chemists several ways to build on it.

In Indonesian laboratories, compounds like this one are relevant to chemists working in synthetic organic chemistry, heterocyclic chemistry and materials science. University research groups may use it to prepare new pyrazoline or pyrazole derivatives, or to study how substituents change fluorescence behaviour. Research institutions working on functional organic materials may use it as a model compound for studying conjugated heterocycles. AMI Scientific supplies the TCI product (catalogue P1951) to support this kind of synthesis and characterisation work.

• Heterocyclic synthesis: the 2-pyrazoline ring with N-phenyl and C-mesityl substituents works as a building block for preparing more complex heterocyclic derivatives.
• Photophysical studies: 1,3-diaryl-2-pyrazolines are known to fluoresce, so this compound can be used to examine emission behaviour and how substituents change it.
• Optoelectronic materials research: the conjugated link between nitrogen and the aromatic rings supports studies of charge transport and emission in candidate organic materials.
• Structure–property relationship studies: the bulky mesityl group adds steric hindrance, so researchers can see how planarity and intermolecular interactions affect molecular properties.
• Oxidation to pyrazoles: the pyrazoline ring can be oxidised to the corresponding pyrazole, making the compound a useful starting point for comparing the two related ring systems.

Keep the compound in its original, tightly closed container in a cool, dry and well-ventilated place, away from direct light, heat sources and incompatible substances such as strong oxidising agents. Follow the storage conditions on the TCI label and Safety Data Sheet. Use the compound in a fume hood or a well-ventilated area and wear standard personal protective equipment, including gloves, safety glasses and a lab coat. Avoid creating or breathing in dust, and avoid contact with skin and eyes. Label any transferred portions clearly. Dispose of waste in line with institutional and local regulations for chemical waste.

—