Pyrazine-2,5-dicarboxylic Acid from TCI (product code P2932, CAS 122-05-4) is a heterocyclic dicarboxylic acid. It consists of a pyrazine ring with two carboxyl groups on opposite positions of the ring. It belongs to the family of heterocyclic building blocks used across chemistry laboratories. Its main roles are as a ligand in coordination chemistry, as a monomer or linker in the synthesis of porous materials, and as a starting material for pyrazine derivatives in organic and medicinal chemistry.
Researchers choose this compound mainly because its molecule is symmetrical and linear. The two carboxylate groups face each other across the ring, and the pyrazine ring adds two nitrogen atoms. Together these give several metal-binding sites in one molecule. That makes the compound well suited to building coordination polymers and metal-organic frameworks (MOFs) with ordered structures. The carboxyl groups can also be turned into esters, amides, or acyl chlorides for further synthesis, so one reagent can serve many synthetic routes.
In Indonesian laboratories, this compound is relevant to research on porous materials, heterogeneous catalysts, and adsorbents for purification. University chemistry departments, materials science groups, and research institutes can use it for early ligand screening and for larger framework syntheses. It comes in 5g and 25g packs. Researchers can pick the amount that fits their work, from small first trials to scaled-up material preparation, without buying more than they need.
- Coordination chemistry ligand: the two opposed carboxylate groups and two ring nitrogen atoms give several metal-binding sites, which makes it a versatile ligand for studying metal complexes.
- Metal-organic framework (MOF) synthesis: its symmetrical, linear geometry makes it a good linker for building ordered porous frameworks with predictable connectivity between metal nodes.
- Coordination polymer research: the multiple binding sites let the molecule bridge metal centers into extended chains or networks, which is useful for studying structure and material properties.
- Synthesis of pyrazine derivatives: the carboxyl groups can be converted into esters, amides, or acyl chlorides, giving a practical starting point for new pyrazine-based compounds in organic chemistry.
- Medicinal chemistry building block: as a functionalized heterocycle, it can serve as a scaffold for preparing pyrazine-containing intermediates used in exploratory medicinal chemistry and compound library work.
| Brand | TCI (product code P2932) |
|---|---|
| CAS number | 122-05-4 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Heterocyclic Building Blocks |
| Pack sizes | 5g and 25g |
| Physical form | refer to the product label and the manufacturer's documentation |
| Storage | follow the storage conditions on the TCI label and Safety Data Sheet (SDS) |
Keep Pyrazine-2,5-dicarboxylic Acid in its original, tightly closed manufacturer container. Store it in a cool, dry, well-ventilated place, away from direct sunlight, moisture, and incompatible substances, as stated on the product label and the Safety Data Sheet. If you transfer material, use clean, dry, chemically compatible containers with clear labels. Handle the compound following good laboratory practice. Wear suitable gloves, safety glasses, and a lab coat, and avoid creating or breathing dust; work in a fume hood or a well-ventilated area. Read the TCI Safety Data Sheet before use, and follow local regulations for chemical waste disposal.
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