Sulfanilic Acid TCI S0120

Chemical Identity

CAS No.: 121-57-3
PubChem: CID 8479·SID 87575730
Formula: C6H7NO3S
Molecular weight: 173.19 g/mol
Purity: >99.0%(HPLC)(T)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 4-aminobenzenesulfonic acid
SMILES: C1=CC(=CC=C1N)S(=O)(=O)O
InChIKey: HVBSAKJJOYLTQU-UHFFFAOYSA-N

Rp 505.050,00

~~Rp 352.800,00~~ Rp 505.050,00

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Berat 25g 500g

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Sulfanilic Acid from TCI is 4-aminobenzenesulfonic acid, an aromatic compound with an amine group and a sulfonic acid group in the para position. TCI lists it among its non-heterocyclic building blocks. In the laboratory, sulfanilic acid is a classic starting material for synthesizing azo dyes, including the indicator methyl orange. It is also one of the reagent components used to determine nitrite by colorimetry, so it is a common item in both synthetic and analytical work.

Sulfanilic acid exists as a zwitterion in the solid state: the strong sulfonic acid group gives up a proton to the amine group on the same molecule. This structure makes the compound fairly stable and easy to handle as a solid. Its aromatic amine group can be diazotized with nitrite, and the diazonium salt that forms can then be coupled with electron-rich aromatic compounds to give azo dyes. The sulfonic acid group makes the final product soluble in water, which the dye industry values highly. Because it is both reactive and practical to handle, chemists choose it for teaching labs as well as for routine analysis.

In Indonesian laboratories, sulfanilic acid is used in university organic chemistry practicals, especially the methyl orange synthesis experiment, which is a standard part of the curriculum. Students use it to learn diazotization and azo coupling with a reaction that clearly shows when it has worked. Water testing laboratories also use sulfanilic acid in colorimetric reagents to determine nitrite. The material also serves research groups that need a reliable non-heterocyclic aromatic building block.

TCI brochures (PDF)

Reactive Oxygen Species (ROS) and Oxidative Stress Research Reagents 2026-04-23 · p. 1
Reagents for Biological Research 2025-03-11 · p. 36

Related TCI products

Azo dye synthesis: the aromatic amine group diazotizes with nitrite, and the diazonium salt couples with electron-rich aromatics to form azo dyes that the sulfonic acid group makes water-soluble.
Methyl orange preparation: sulfanilic acid is the classic starting material for this indicator, so it is the standard choice when preparing methyl orange in teaching or research laboratories.
Colorimetric nitrite determination: it is one of the reagent components in nitrite tests, where diazotization followed by coupling produces a colored product that can be measured by colorimetry.
University organic chemistry practicals: as a stable, easy-to-handle solid, it suits student experiments that demonstrate diazotization, azo coupling, and zwitterion behavior in a single procedure.
Organic synthesis building block: TCI classifies it as a non-heterocyclic building block, and its amine and sulfonic acid groups in the para position give researchers two distinct functional handles for building larger molecules.

Brand	TCI (product code S0120)
CAS number	121-57-3
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	as listed on this product page
Physical form	solid (exists as a zwitterion in the solid state)
Storage	keep in a tightly closed container in a cool, dry place; follow the TCI label and Safety Data Sheet

Store sulfanilic acid in its original, tightly closed container in a cool, dry, well-ventilated area, away from direct sunlight and moisture. Keep it apart from strong oxidizing agents and incompatible chemicals, and reseal the container promptly after each use. Wear standard laboratory protective equipment when handling it, including gloves, safety glasses, and a lab coat. Avoid creating or breathing in dust by weighing it carefully, preferably in a fume hood or a ventilated weighing area. Wash your hands thoroughly after handling. Always check the TCI Safety Data Sheet for full hazard information, first-aid measures, and disposal instructions before use.

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