N-Trimethylsilylimidazole [Trimethylsilylating Reagent] (CAS 18156-74-6) is a high-quality chemical from TCI, supplied as Reagent Grade / for Synthesis.
Application: Used as a silylating reagent for hydroxyl-group protection and GC derivatisation.
Specifications:
- Molecular formula: C6H12N2Si
- CAS number: 18156-74-6
- Purity: >98.0%(T)
- TCI product code: T0585
Synonyms: TMS-Imidazole; SIM; TMSI
Available from AMI Scientific, the authorised TCI distributor in Indonesia. Contact us for pricing and stock availability — we ship throughout Indonesia.
Advantages (TCI brochure)
- Reacts only with hydroxy groups, sugars, steroids and uric acids
- Hindered hydroxy groups: use BSA and TMCS together with SIM
TCI brochures (PDF)
- GC Derivatization Reagents 2026-03-25 · p. 2
- DualSeal ― Airtight-Double-Cap Bottled Reagents 2024-08-13 · p. 6
- Protecting Agents 2025-03-25 · p. 5
- Please inquire for pricing and availability of listed products to our local sales representatives. Si Si Et 2026-07-16 · p. 10
Related TCI products
- TCI T0693 18156-74-6 N-Trimethylsilylimidazole Kit SIM 1 mL * 8 / Reaction vial, capacity 2 mL * 8 [Trimethylsilylating Reagent]
- TCI B1043 54925-64-3 1-(tert-Butyldimethylsilyl)imidazole [tert-Butyldimethylsilylating Agent]
- TCI T1535 43112-38-5 3-Trimethylsilyl-2-oxazolidinone [Trimethylsilylating Reagent]
- TCI T1277 13368-42-8 N-(Trimethylsilyl)morpholine
- TCI A0694 2466-76-4 N-Acetylimidazole
- TCI D1516 62365-34-8 1-(Dimethylethylsilyl)imidazole [Dimethylethylsilylating Agent]
From the TCI brochure
- Steroids: 0.2 mL SIM added to 1-5 mg substrate in 0.1 mL pyridine, 0.5-1 hour at room temperature
- Ketosteroids: after 3 hours, add 0.2 mL BSA and leave 2 more hours at room temperature
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Product Categories
- Building BlocksHeterocyclic Building BlocksNon-Halogenated Heterocyclic Building Blocks
- Synthetic ReagentsProtection, Deprotection, DerivatizationProtecting and Derivatizing Reagents [Synthetic Reagents]
- Organometallic ReagentsOrganosilicon [Organometallic Reagents]Organosilicon Compounds (Other) [Organosilicon]
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