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TCI

CAS 18156-74-6

N-Trimethylsilylimidazole [Trimethylsilylating Reagent] TCI T0585

N-Trimethylsilylimidazole [Trimethylsilylating Reagent] TCI T0585

Chemical Identity

CAS No.
18156-74-6
PubChem
CID 28925·SID 87576483
Formula
C6H12N2Si
Molecular weight
140.26 g/mol
Purity
>98.0%(T)
Reference databases
ChEBI·ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
imidazol-1-yl(trimethyl)silane
SMILES
C[Si](C)(C)N1C=CN=C1
InChIKey
YKFRUJSEPGHZFJ-UHFFFAOYSA-N
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N-Trimethylsilylimidazole [Trimethylsilylating Reagent] (CAS 18156-74-6) is a high-quality chemical from TCI, supplied as Reagent Grade / for Synthesis.

Application: Used as a silylating reagent for hydroxyl-group protection and GC derivatisation.

Specifications:

  • Molecular formula: C6H12N2Si
  • CAS number: 18156-74-6
  • Purity: >98.0%(T)
  • TCI product code: T0585

Synonyms: TMS-Imidazole; SIM; TMSI

Available from AMI Scientific, the authorised TCI distributor in Indonesia. Contact us for pricing and stock availability — we ship throughout Indonesia.

Advantages (TCI brochure)

  • Reacts only with hydroxy groups, sugars, steroids and uric acids
  • Hindered hydroxy groups: use BSA and TMCS together with SIM

From the TCI brochure

  • Steroids: 0.2 mL SIM added to 1-5 mg substrate in 0.1 mL pyridine, 0.5-1 hour at room temperature
  • Ketosteroids: after 3 hours, add 0.2 mL BSA and leave 2 more hours at room temperature

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