Thiophene-3-acetic Acid TCI T1152

Chemical Identity

CAS No.: 6964-21-2
PubChem: CID 23404·SID 87576940
Formula: C6H6O2S
Molecular weight: 142.18 g/mol
Purity: >98.0%(T)
Reference databases: ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 2-thiophen-3-ylacetic acid
SMILES: C1=CSC=C1CC(=O)O
InChIKey: RCNOGGGBSSVMAS-UHFFFAOYSA-N

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Berat 5g 25g

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Thiophene-3-acetic Acid (TCI T1152, CAS 6964-21-2) is a compound built around a thiophene ring carrying an acetic acid group at the three position. It combines a sulfur-containing aromatic heterocycle with a carboxylic acid group that is easy to modify chemically. In the laboratory it serves as a functional monomer and as a synthetic building block, and it is used most often in research on conductive polymers based on polythiophene, where an acid side group is needed so the polymer can be linked to other molecules.

The carboxylic acid on the side chain provides an anchoring point for forming esters and amides, so the resulting polymers or thin films can be chemically modified after they are made. The thiophene ring can be polymerized either oxidatively or electrochemically, producing a conjugated backbone that becomes conductive after doping. This pairing of a polymerizable ring with a reactive side group is why the compound is chosen for biosensor interfaces, electrode coatings, and materials that need reactive functional groups. Substitution at the three position of thiophene is also commonly used to obtain polymers with good structural regularity.

For Indonesian laboratories, this material is relevant to polymer chemistry, electrochemistry, and materials science, including sensor development. Research groups working on conductive coatings, modified electrodes, or functionalized thin films can use it as a starting point for their syntheses. It is supplied in 5 g and 25 g packs, which lets a laboratory match the quantity to its scale of work, whether that is a small exploratory study or a longer series of experiments.

TCI brochures (PDF)

Thiophenes 2026-06-29 · p. 9

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Conductive polymer research: the thiophene ring can be polymerized oxidatively or electrochemically into a conjugated polythiophene backbone, and the acetic acid side group adds a functional handle to the resulting polymer.
Biosensor interface development: the carboxylic acid group can be coupled to biomolecules through amide formation, which makes this monomer a practical choice for building reactive sensing layers on electrodes.
Electrode coating and surface modification: electropolymerization of the thiophene ring forms thin films on electrode surfaces, and the acid groups in those films can be modified chemically afterward.
Ester and amide synthesis: the carboxylic acid on the side chain reacts to form esters and amides, so the compound works as a heterocyclic building block for preparing a range of thiophene derivatives.
Functional materials and materials science studies: researchers who need conjugated materials with reactive groups can use this monomer, since substitution at the three position supports polymers with good structural regularity.

Brand	TCI
CAS number	6964-21-2
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes	5 g and 25 g
Physical form	—
Storage	keep in a tightly closed container and follow the storage instructions on the label and in the supplier's safety data sheet

Product code: T1152

Store Thiophene-3-acetic Acid in its original, tightly closed container in a clean, dry place away from heat, direct sunlight, and incompatible chemicals. Follow the specific storage conditions printed on the label and in the safety data sheet. After each use, close the container promptly to limit exposure to air and moisture. As with other organic acids and sulfur-containing heterocycles, handle the material in a well-ventilated area or a fume hood, and wear gloves, safety glasses, and a laboratory coat. Avoid inhaling dust and avoid contact with skin and eyes. Weigh it with clean, dry tools, and label any solutions you prepare with the date and contents. Dispose of waste according to your institution's chemical waste procedures and local regulations.

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