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TCI

CAS 1885-46-7

Difluoromethyl Trifluoromethanesulfonate TCI T4382

Difluoromethyl Trifluoromethanesulfonate TCI T4382

Chemical Identity

CAS No.
1885-46-7
Purity
>98.0%(GC)
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Difluoromethyl Trifluoromethanesulfonate (CAS 1885-46-7) is a high-quality chemical from TCI, supplied as GC Grade / for Synthesis.

Application: Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.

Specifications:

  • Molecular formula: C2HF5O3S
  • CAS number: 1885-46-7
  • Purity: >98.0%(GC)
  • TCI product code: T4382

Synonyms: Difluoromethyl Triflate; Trifluoromethanesulfonic Acid Difluoromethyl Ester

Available from AMI Scientific, the authorised TCI distributor in Indonesia. Contact us for pricing and stock availability — we ship throughout Indonesia.

Advantages (TCI brochure)

  • Realizes efficient and selective introduction of difluoromethyl (CHF2) groups into hydroxy groups in phenols.
  • Enables reactions to proceed within minutes at room temperature due to its high reactivity.
  • Has exceptional functional group tolerance with broad applicability to complex molecular structures.
  • Allows one-pot incorporation of difluoromethoxy groups from arylboronic acids, aryl halides, and arenes.

From the TCI brochure

  • Synthesis of difluoromethyl ethers as an alternative to HCF2Cl
  • Introduction of CHF2 groups into hydroxy groups in phenols
  • One-pot incorporation of difluoromethoxy groups from arylboronic acids, aryl halides, and arenes

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Data from the TCI brochure

Waktu reaksi2 min. (r.t.)

Source: TCI brochure RR228 (2026-04-30)

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References cited in the TCI brochure

  1. Patrick S. Fier. Synthesis of Difluoromethyl Ethers with Difluoromethyltriflate Angewandte Chemie International Edition, 2013. doi:10.1002/anie.201209250
  2. Gregory Landelle. Tri- and difluoromethoxylated N-based heterocycles − Synthesis and insecticidal activity of novel F3CO- and F2HCO-analogues of Imidacloprid and Thiacloprid Journal of Fluorine Chemistry, 2017. doi:10.1016/j.jfluchem.2017.08.006