Collection: Co-Translational Modification

Co-Translational Modification — compiles non-natural amino acids and their derivatives, such as TCO-tagged lysine, azidonorleucine, and modified tyrosine, designed to be incorporated into protein chains during translation for labeling and bioorthogonal protein studies.

Non-natural amino acids in this category are used in genetic code expansion techniques to incorporate reactive groups such as azide, alkyne, or TCO at specific positions in protein chains during translation. Researchers in proteomics and chemical biology use them for selective labeling of target proteins via click reactions or bioorthogonal ligation without disrupting the native protein structure.

Example products in this collection: TCI T4126 1380349-88-1 N-(4E)-TCO-L-lysine, TCI B6511 1262681-31-1 Biotin-PEG4-Alkyne, TCI A3554 1454334-76-9 L-Azidonorleucine Hydrochloride, TCI C3770 7423-93-0 H-Tyr(3-Cl)-OH, TCI A3550 120042-14-0 L-Azidohomoalanine, TCI C3952 939-69-5 6-Hydroxybenzo[d]thiazole-2-carbonitrile, TCI A2171 1946-82-3 Nalpha-Acetyl-L-lysine, TCI D0213 300-38-9 3,5-Dibromo-L-tyrosine.

Please check the compatibility of reactive groups (azide, alkyne, or TCO) with the protein expression system used, as well as the purity and salt form of the amino acid before use in experiments. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories at the same level under Proteomics, often used together in a single laboratory workflow:

• Post-Translational Modification
• Protein Sample Preparation
• Protein Electrophoresis
• Protein Determination
• Protein Interaction

Back to Proteomics. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.