HPLC Derivatization Reagents

HPLC Derivatization Reagents — a collection of derivatization reagents such as dansyl chloride, dabsyl chloride, and aminothiol or aminopyridine compounds that react with target functional groups to form detectable products with high sensitivity and selectivity in chromatography.

These derivatization reagents are used before or after HPLC separation to convert analytes that are difficult to detect, such as amino acids, alcohols, or amines, into fluorescent or colored derivatives that are easily analyzed with UV or fluorescence detectors. Analytical chemistry researchers use labels such as 9-(bromomethyl)acridine or dansyl chloride to improve the sensitivity of compound quantification in biological and environmental samples.

Examples of products in this collection: TCI A0267 137-07-5 2-Aminobenzenethiol, TCI D0005 605-65-2 Dansyl Chloride (10% in Acetone), TCI A0411 504-29-0 2-Aminopyridine, TCI D0656 605-65-2 Dansyl Chloride, TCI B1926 1556-34-9 9-(Bromomethyl)acridine [for HPLC Labeling], TCI D1382 56512-49-3 Dabsyl Chloride [N-Protecting Agent for Peptides Research], TCI B0949 17683-09-9 1-Benzyl-3-p-tolyltriazene [for Esterification], TCI D1653 7612-98-8 4-(Dimethylamino)azobenzene 4'-Isothiocyanate.

Consider the functional group of the analyte to be derivatized (amine, thiol, or carboxylic acid), the reagent's compatibility with the detection method (UV, fluorescence, or electrochemical), and the storage conditions of reagent solutions, which are sensitive to moisture or light. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under HPLC, often used together in a single laboratory workflow:

Back to HPLC. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team, the official distributor of TCI Japan in Indonesia, to check availability and lead time directly from Japan.

Related TCI catalogs (PDF)

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