Collection: Peptide Nucleic Acid (PNA) Monomers
Peptide Nucleic Acid (PNA) Monomers — contains building block monomers for the synthesis of peptide nucleic acid (PNA), namely nucleic acid analogs with a pseudopeptide backbone that carry nucleobases protected by Fmoc and Bhoc groups. This group serves as the raw material for solid-phase PNA synthesis.
Fmoc-PNA monomers with adenine, guanine, cytosine, and thymine bases are used in solid-phase synthesis of PNA oligomers that bind to target DNA or RNA through Watson-Crick base pairing, but with affinity and stability different from natural nucleic acids. Nucleic acid chemistry researchers and molecular probe developers use this group to make synthetic antisense oligomers and hybridization probes in molecular biology research.
Example products in this collection: TCI D5934 169396-92-3 Fmoc-PNA-T-OH, TCI D5931 186046-82-2 Fmoc-PNA-A(Bhoc)-OH, TCI D5933 186046-83-3 Fmoc-PNA-G(Bhoc)-OH, TCI D5932 186046-81-1 Fmoc-PNA-C(Bhoc)-OH.
Select the appropriate base protecting group (Bhoc for exocyclic amino bases, no additional protecting group for thymine) and an Fmoc strategy compatible with the solid-phase synthesis protocol being used. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.
Other categories at the same level under Nucleic Acid Chemistry, often used together in a single laboratory workflow:
- Phosphorylating Agents and Phosphorothioating Agents [Nucleic Acid Synthesis]
- Coupling Activators and Condensing Agents [Nucleic Acid Synthesis]
- Protecting Agents for Hydroxy and Amino Groups [Nucleic Acid Synthesis]
- Nucleoside Phosphoramidites [Nucleic Acid Synthesis]
- Sulfur Transfer Reagents [Nucleic Acid Synthesis]
Back to Nucleic Acid Chemistry. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.