Collection: Nucleoside Phosphoramidites [Nucleic Acid Synthesis]
Nucleoside Phosphoramidites [Nucleic Acid Synthesis] — covers DMT-protected nucleosides with an active phosphoramidite at the 3'-hydroxyl position, including modified bases such as 2'-O-MOE and pseudouridine analogs. These building blocks are specifically designed for automated oligonucleotide assembly.
Nucleoside Phosphoramidites [Nucleic Acid Synthesis] are used by molecular biology and nucleic acid chemistry researchers for the synthesis of oligonucleotides and antisense oligos on solid-phase synthesizers through repeated phosphoramidite coupling cycles. 2'-O-MOE derivatives, such as those of cytosine, uracil, adenine, and guanine, are commonly used to enhance the stability of modified oligos, while phosphoramidites with modified bases such as 1-methylpseudouridine are used in the assembly of specialized synthetic RNA.
Example products in this collection: TCI M3374 251647-54-8 DMT-2'-O-MOE-rC(Bz) Phosphoramidite, TCI D5701 102212-98-6 DMT-dC(bz) Phosphoramidite, TCI M3373 163759-97-5 DMT-2'-O-MOE-rU Phosphoramidite, TCI D5702 98796-51-1 DMT-dT Phosphoramidite, TCI M3372 251647-53-7 DMT-2'-O-MOE-rA(Bz) Phosphoramidite, TCI D5703 199593-09-4 DMT-2'-O-methyl-rC(Ac) Phosphoramidite, TCI M3371 251647-55-9 DMT-2'-O-MOE-rG(Ib) Phosphoramidite, TCI D5704 110764-79-9 DMT-2'-O-methyl-rU Phosphoramidite.
Consider the protecting groups (benzoyl, isobutyryl), the coupling purity of the phosphoramidite, and compatibility with the automated oligonucleotide synthesis protocol being used. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.
Other categories at the same level under Nucleic Acid Chemistry, often used together in one laboratory workflow:
- Phosphorylating Agents and Phosphorothioating Agents [Nucleic Acid Synthesis]
- Coupling Activators and Condensing Agents [Nucleic Acid Synthesis]
- Protecting Agents for Hydroxy and Amino Groups [Nucleic Acid Synthesis]
- Peptide Nucleic Acid (PNA) Monomers
- Sulfur Transfer Reagents [Nucleic Acid Synthesis]
Back to Nucleic Acid Chemistry. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team, the official distributor of TCI Japan in Indonesia, for availability checks and lead times directly from Japan.