Atorvastatin Lactone (TCI A3114) is a chemical compound widely used in pharmaceutical research and biochemical studies. It serves as a key reagent in experimental settings, particularly in the development and testing of lipid-lowering drugs. This compound is a lactone derivative of atorvastatin, a well-known HMG-CoA reductase inhibitor used in the treatment of hyperlipidemia. In laboratory environments, it plays a crucial role in the synthesis of active pharmaceutical ingredients and in the evaluation of biological activity. Its chemical structure and functional properties make it an essential tool for researchers exploring the mechanisms of cholesterol metabolism and related therapeutic applications.
The stability and high purity of Atorvastatin Lactone make it a preferred choice for scientific research. It exhibits excellent solubility in organic solvents such as ethyl acetate and ethanol, which facilitates its use in various analytical and synthetic procedures. Its chemical specificity ensures reliable results in experiments involving enzyme activity, molecular structure analysis, and drug interaction studies. These properties contribute to its widespread use in both academic and industrial research settings, where precision and reproducibility are paramount.
In Indonesian laboratories, Atorvastatin Lactone is commonly used in pharmacological, biochemical, and pharmaceutical research. It supports studies on drug metabolism, enzyme inhibition, and the development of new therapeutic agents. Its availability and consistent quality make it a valuable resource for researchers working on lipid-related disorders and cardiovascular health. Its role in both basic and applied research underscores its importance in the scientific community.
TCI brochures (PDF)
- Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 22
- Reagents for Biological Research 2025-03-11 · p. 45
Related TCI products
- TCI A2476 344423-98-9 Atorvastatin Calcium Salt Trihydrate
- TCI L0005 96-82-2 Lactobionic Acid (mixture of Acid form and Lactone form)
- TCI B3346 41859-67-0 Bezafibrate
- TCI R0180 147098-20-2 Rosuvastatin Calcium
- TCI P2071 147526-32-7 Pitavastatin Calcium (contains 15% Water at maximum)
- TCI P1796 81131-70-6 Pravastatin Sodium
- Pharmacological research utilizes Atorvastatin Lactone to study the mechanisms of HMG-CoA reductase inhibition and its impact on lipid metabolism.
- Biochemical studies employ this compound to investigate enzyme activity and substrate interactions in metabolic pathways.
- Pharmaceutical research uses it as a starting material for the synthesis of active pharmaceutical ingredients and drug derivatives.
- Molecular structure analysis benefits from its chemical specificity, allowing precise characterization of drug molecules and their interactions.
- Drug development programs incorporate it to evaluate the efficacy and safety of new lipid-lowering agents in preclinical trials.
| Brand | TCI |
|---|---|
| CAS number | 125995-03-1 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents |
| Pack sizes | Available in various quantities as per standard laboratory supply |
| Physical form | Solid powder |
| Storage | Store in a cool, dry place away from direct light |
Atorvastatin Lactone should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to keep it in a sealed container to minimize exposure to moisture and air, which could affect its purity. Suitable storage conditions include a controlled laboratory environment with a temperature range of 15-25°C and humidity levels below 60%. General laboratory precautions include avoiding contact with incompatible substances and ensuring proper ventilation when handling. Due to its chemical nature, it is advisable to use appropriate personal protective equipment, such as gloves and safety goggles, during handling. Proper storage and handling practices help ensure the compound remains effective and safe for use in research applications.
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Product Categories
- Biochemicals and ReagentsPharmaceutical Research Reagents (for Experimental Use)Antilipemic Ingredients (for Research and Experimental Use)
- Pharmaceutical Development and Drug Discovery ResearchPharmaceutical Research Reagents (for Experimental Use)Antilipemic Ingredients (for Research and Experimental Use)
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