• 139332-66-4 NBD-PZ (=4-Nitro-7-piperazino-2,1,3-benzoxadiazole) [for HPLC Labeling] - AMI Scientific
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TCI

CAS 139332-66-4

NBD-PZ (=4-Nitro-7-piperazino-2,1,3-benzoxadiazole) [for HPLC Labeling] TCI A5554

NBD-PZ (=4-Nitro-7-piperazino-2,1,3-benzoxadiazole) [for HPLC Labeling] TCI A5554

Chemical Identity

Other names
NBD-PZ
CAS No.
139332-66-4
PubChem
CID 10586684·SID 87563172
Formula
C10H11N5O3
Molecular weight
249.23 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
4-nitro-7-piperazin-1-yl-2,1,3-benzoxadiazole
SMILES
C1CN(CCN1)C2=CC=C(C3=NON=C23)[N+](=O)[O-]
InChIKey
MVLWYDGJBGPXOL-UHFFFAOYSA-N
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NBD-PZ (4-Nitro-7-piperazino-2,1,3-benzoxadiazole) is a fluorescent compound widely used in biochemical and molecular analysis applications within laboratory settings. As a fluorescent label, it plays a crucial role in identifying and tracking specific molecules during analytical procedures. Its ability to emit light at specific wavelengths when exposed to light sources makes it an essential tool for fluorescence-based detection methods. This compound is particularly valuable in high-performance liquid chromatography (HPLC) applications, where it is used to label and monitor compounds with high precision. Its utility extends across various scientific disciplines, including biochemistry, pharmacology, and environmental analysis, due to its versatility and reliability.

NBD-PZ is preferred for its stable fluorescence properties and high light intensity, which ensure accurate and consistent results during analysis. The compound’s chemical stability under typical laboratory conditions enhances its shelf life and minimizes the risk of degradation, making it a reliable choice for long-term use. Additionally, its ability to bind to a wide range of molecules allows it to be adapted for multiple applications, from protein labeling to nucleic acid detection. These characteristics make it a favored choice among researchers seeking precise and dependable fluorescent labeling solutions.

In Indonesian laboratories, NBD-PZ is commonly used in biochemistry and pharmacology research, as well as environmental analysis. Its application in HPLC labeling supports the study of complex molecular interactions and the identification of compounds in various sample matrices. The compound’s reliability and performance make it an essential component of many research workflows in both academic and industrial settings.

Advantages (TCI brochure)

  • Green-yellow fluorescence from NBD core
  • Labeled to carboxy groups by amide bond formation using a coupling agent

TCI brochures (PDF)

Related TCI products

  • High-Performance Liquid Chromatography (HPLC) benefits from NBD-PZ as a fluorescent label, allowing precise detection and quantification of compounds in complex mixtures.
  • Biochemical research utilizes NBD-PZ for molecular tracking and identification, enhancing the accuracy of analytical procedures in laboratory settings.
  • Pharmacological studies employ NBD-PZ to label and monitor drug molecules, supporting drug development and mechanism of action research.
  • Environmental analysis leverages NBD-PZ for detecting pollutants and contaminants in water and soil samples, offering sensitive and reliable detection.
  • Molecular biology applications use NBD-PZ for labeling nucleic acids and proteins, facilitating advanced research in genetic and cellular processes.

From the TCI brochure

  • Labeling of carboxy groups

Brand TCI
CAS number 139332-66-4
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Fluorescent Probes, Fluorescent Labels, Fluorescent Stains
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid (as per standard product description)
Storage Store in a cool, dry place away from light

Data from the TCI brochure

λex,maxca. 470 nm
λem,maxca. 530 nm

Source: TCI brochure LL039 (2025-11-18)

NBD-PZ should be stored in a cool, dry environment, away from direct light to maintain its chemical stability and fluorescence properties. It is recommended to use airtight containers to prevent moisture absorption and contamination. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper labeling of containers is essential for safe storage and retrieval. Regular monitoring of storage conditions ensures the compound remains effective for its intended applications. All handling should follow standard laboratory safety protocols to minimize risks and maintain the integrity of the material.

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Product Categories

Life Science

Analytical Chemistry

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